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Investigation of the Effect of Age and Injury Severity on Short-term Intra-hospital Outcomes After Surgical Stabilized Rib Fractures

Investigation of the Effect of Age and Injury Severity on Short-term Intra-hospital Outcomes After Surgical Stabilized Rib Fractures

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06464302
Enrollment
1064
Registered
2024-06-18
Start date
2024-05-01
Completion date
2025-12-31
Last updated
2026-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Rib Fracture Multiple, Rib Fractures, Rib Trauma, Thorax; Fracture

Keywords

Surgical stabilisation of rib fractures (SSRF)

Brief summary

The study aims to investigate the effect of surgical stabilisation of rib fractures (SSRF) on clinical outcomes measured during the hospital stay (mortality, days on a mechanical ventilator, intensive care unit and hospital length of stay, rate of complications). Furthermore, the effect of the patients age and overall injury severity on the outcomes after SSRF will be investigated. We hypothesise that the combination of high age and high injury severity will lead to worse outcomes after SSRF.

Interventions

Surgical stabilisation of rib fractures using any fixation technique (including but not limited to plate fixation, intramedullary fixation, wire fixation) via any operative approach (including but not limited to open external approach, minimally invasive approach, thoracoscopic approach, thoracotomy approach).

Any supportive or specific treatment of rib fractures excluding surgical stabilisation of rib fractures. This includes, but is not limited to analgesia, physiotherapy, non-invasive ventilation, mechanical ventilation, oxygen-supplementation

Sponsors

University Hospital Muenster
Lead SponsorOTHER

Study design

Observational model
CASE_CONTROL
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
0 Years to 100 Years
Healthy volunteers
No

Inclusion criteria

* Patients of the University Hospital Muenster * Coded serial rib fractures (ICD S22.4 and S22.5) * Treatment for the rib fractures between 2019 and 2023

Exclusion criteria

* pathological rib fractures (due to suspected malignancy)

Design outcomes

Primary

MeasureTime frameDescription
In hospital-mortalityFrom injury up to initial hospital discharge or death, whichever came first, assessed up to 2 month.Mortality rate from injury to initial hospital discharge, binary
Intensive care unit length of stayFrom injury up to initial hospital discharge or death, whichever came first, assessed up to 2 month.The duration in days a patient spent in the intensive care unit from the time of hospital admission to the time of initial hospital discharge.

Secondary

MeasureTime frameDescription
Intubation rateFrom injury up to initial hospital discharge or death, whichever came first, assessed up to 2 month.Proportion of patients intubated at any time
Multi-organ failureFrom injury up to initial hospital discharge or death, whichever came first, assessed up to 2 month.Rate of Multi-organ failure
Single organ failureFrom injury up to initial hospital discharge or death, whichever came first, assessed up to 2 month.Rate of single organ failure
SepsisFrom injury up to initial hospital discharge or death, whichever came first, assessed up to 2 month.Rate of Sepsis
Lung-failureFrom injury up to initial hospital discharge or death, whichever came first, assessed up to 2 month.Rate of Lung-failure
Clinical outcomeAt the time point of initial hospital discharge or at death, whichever came first, assessed up to 2 month.Clinical outcome according to the Glasgow outcome scale (GOS)
Duration of hospital stayFrom injury up to initial hospital discharge or death, whichever came first, assessed up to 2 month.Duration of hospital stay in days from injury to initial discharge

Countries

Germany

Contacts

STUDY_DIRECTORSteffen Rosslenbroich, PD Dr. med.

Department for trauma, hand and reconstructive surgery, University hospital Muenster

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Apr 30, 2026