Rib Fractures, Thorax; Fracture
Conditions
Keywords
surgical stabilisation of rib fractures, non-ventilator-dependent
Brief summary
The aim of the study is to investigate the effect of surgical stabilisation of rib fractures on clinical outcomes in patients that are not dependent on mechanical ventilation at the time of the treatment decision. To this end, data on all eligible patients will be extracted from the TraumaRegister® DGU. Baseline demographics will be analysed using descriptive statistics. Propensity matching will be conducted between the operative cohort (receiving SSRF by any technique) and the conservative cohort (not receiving SSRF). The effect of SSRF on the outcome variables will then be assessed using appropriate statistical tests.
Interventions
Surgical stabilisation of rib fractures using any fixation technique (including but not limited to plate fixation, intramedullary fixation, wire fixation) via any operative approach (including but not limited to open external approach, minimally invasive approach, thoracoscopic approach, thoracotomy approach).
Any supportive or specific treatment of rib fractures excluding surgical stabilisation of rib fractures. This includes, but is not limited to analgesia, physiotherapy, non-invasive ventilation, mechanical ventilation, oxygen-supplementation.
Sponsors
TraumaRegister® DGU
University Hospital Muenster
Study design
Observational model
CASE_CONTROL
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
10 Years to 100 Years
Healthy volunteers
No
Inclusion criteria
* Rib AIS of ≥ 3 * Initial hospital treatment
Exclusion criteria
* Intubated preclinically or in the emergency department * Glasgow coma scale (GCS) \< 9 at the time of the primary survey in the emergency department * No in-patient hospital management
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| In-hospital mortality | From injury up to initial hospital discharge or death, whichever came first, assessed up to 2 month. | Number of patients who died in the hospital and mortality rate up to hospital discharge |
| Duration of mechanical ventilation | From injury up to initial hospital discharge or death, whichever came first, assessed up to 2 month. | The duration in hours a patient spent intubated from the time of hospital admission to the time of initial hospital discharge |
| Duration of intensive care unit stay. | From injury up to initial hospital discharge or death, whichever came first, assessed up to 2 month. | The duration in days a patient spent in the intensive care unit from the time of hospital admission to the time of initial hospital discharge. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Rate of multiorgan failure | From injury up to initial hospital discharge or death, whichever came first, assessed up to 2 month. | The Rate of multiorgan failure from injury to initial hospital discharge |
| Rate of respiratory failure | From injury up to initial hospital discharge or death, whichever came first, assessed up to 2 month. | The Rate of respiratory failure from injury to initial hospital discharge |
| Proportion of patients intubated at any time | From injury up to initial hospital discharge or death, whichever came first, assessed up to 2 month. | Proportion of patients intubated at any time from time of injury to initial hospital discharge |
| Clinical outcome | At the time of initial hospital discharge or death, whichever came first, assessed up to 2 month. | Clinical outcome according to the Glasgow Outcome Scale |
| Rate of sepsis | From injury up to initial hospital discharge or death, whichever came first, assessed up to 2 month. | The Rate of sepsis from injury to initial hospital discharge |
| Duration of hospital stay | From injury up to initial hospital discharge or death, whichever came first, assessed up to 2 month. | Duration of the initial hospital stay in days |
| Rate of single organ failure | From injury up to initial hospital discharge or death, whichever came first, assessed up to 2 month. | The Rate of single organ failure from injury to initial hospital discharge |
Countries
Germany
Outcome results
None listed