Postoperative Acute Kidney Injury
Conditions
Brief summary
To develop and externally validate a risk prediction model for postoperative acute kidney injury (PO-AKI) in elderly patients undergoing major noncardiac surgery, addressing the current gap in predictive tools for this vulnerable population. The endpoint was the occurrence of PO-AKI within seven days following surgery. Diagnoses were based on the Kidney Disease: Improving Global Outcomes (KDIGO) criterion. Potential PO-AKI-related perioperative data were retrieved and extracted from electronic medical record for model derivation and validation. Clinicians may consider implementing this externally validated risk prediction model to stratify elderly patients' PO-AKI risks in the early postoperative phases of noncardiac surgery in elderly patients.
Interventions
OTHERNo intervention
no intervention
Sponsors
Chinese PLA General Hospital
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
65 Years to 120 Years
Healthy volunteers
No
Inclusion criteria
* elderly patients (aged ≥ 65 years) undergoing non-cardiac surgeries
Exclusion criteria
* (1) Patients who underwent endoscopic or transplant procedures; * (2) Patients who underwent surgeries lasting longer than 10 hours; * (3) Patients who had severe preoperative kidney dysfunction, defined as preoperative sCr levels ≥ 353.6 μmol/L, or a baseline estimated Glomerular Filtration Rate (eGFR) \< 15 ml/min per 1.73 m2; * (4) Patients without sCr values at baseline or during follow-up to detect PO-AKI occurrences.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Number of participants with postoperative acute kidney injury | within seven days following surgery | Postoperative acute kidney injury |
Outcome results
None listed