Repetitive Transcranial Magnetic Stimulation in Treatment and Prophylaxis of Chronic Migraine in Patients With no Prophylactic Treatment for the Last 3 Months

Repetitive Transcranial Magnetic Stimulation in Treatment of Chronic Migraine

Status

Recruiting

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT06461767

Acronym

rTMS

Enrollment

Registered

2024-06-17

Start date

2024-01-01

Completion date

2025-01-01

Last updated

2024-06-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic Migraine

Brief summary

Compared with the patients with episodic migraine those with chronic migraine have worst quality of life and more severe headache related disability we investigate Repetitive transcranial magnetic stimulation in treatment and prophylaxis of chronic migraine

Interventions

DEVICEtranscranial magnetic stimulation device

Repetitive transcranial magnetic stimulation parameters: stimulation site: left dorsolateral prefrontal cortex and left motor cortex intensity: 70% of resting motor threshold frequency: 15 Hz number of pulses: 30

Study design

Allocation

NON_RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

SINGLE (Subject)

Intervention model description

the patient will divide into 4 groups first group will receive stimulation over the left motor cortex second group will receive stimulation over left dorsolateral prefrontal cortex third group will receive stimulation over both left motor cortex and left dorsolateral prefrontal cortex fourth group will receive sham stimulation

Eligibility

Sex/Gender

ALL

Healthy volunteers

Inclusion criteria

* A study sample of patients with chronic migraine according to international classification of headache disorders-3 (ICHD-3). * Patients are regular on follow up visits.

Exclusion criteria

* Patients with depression by Hamiliton scale of depression by using its Arabic version Translated by Dr Lotfy Fateem * patients on prophylactic medications for chronic migraine. * pregnancy. * cochlear implants, cardiac pacemaker, and metal body implanted in head-and-neck region. * Patients refused to give informed consent. * History of seizures.

Design outcomes

Primary

Measure	Time frame	Description
improvement of headache severity and number of attacks of headache before and after intervention by visual analogue scale and headache impact test	one month after treatment	improvement of headache severity and number of attacks of headache before and after intervention by visual analogue scale and headache impact test

Countries

Egypt

Contacts

Primary ContactTarek Mohamed

tarikmohamed@med.sohag.edu.eg01025545002

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026