Postoperative Pain, Symptomatic Irreversible Pulpitis
Conditions
Keywords
Pulpitis, Postoperative Pain, VAS
Brief summary
The goal of this randomized clinical trial is to learn the effect of using local corticosteroids and maintaining apical patency in reducing post-preparation pain in patients with acute irreversible pulpitis in molar teeth. The main question it aims to answer is: • How effective are using local corticosteroids and maintaining apical patency in reducing post-preparation pain in patients with acute irreversible pulpitis? Participants will be asked to fill a visual analogue scale to record their pain, after receiving a root canal treatment while using local corticosteroids or not as well as maintaining apical patency or not. Researchers will compare the use of corticosteroids and maintaining apical patency in reducing post-operative pain.
Interventions
PROCEDURENon-corticosteroid injection
no infiltration injection of 0.7 ml of dexamethasone lateral to the involved tooth after anesthesia administration.
DRUGCorticosteroid injection
infiltration injection of 0.7 ml of dexamethasone lateral to the involved tooth after anesthesia administration.
Sponsors
Suez Canal University
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
PREVENTION
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
ALL
Age
21 Years to 60 Years
Healthy volunteers
Yes
Inclusion criteria
* Symptomatic acute irreversible pulpitis in molar teeth. * Normal periapical condition including periapical radiography with minimal widening of periodontal ligament. * Normal probing depth. * No medical condition. * No contraindication for administration of corticosteroids and local anesthesia.
Exclusion criteria
* Facial or oral paresthesia. * Pregnancy & breastfeeding. * Unrestorable tooth. * Marginal periodontal disease. * Presence of a crown on the tooth involved. * Over instrumentation during root canal treatment. * Long-term use of corticosteroids. * False-positive cases of sensibility test with necrosis discovered after gaining access to the tooth. * Cases requiring intrapulpal injection to promote anesthesia.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Post-operative pain | 6, 12, 24, 48, 72 hour and 7 days postoperative intervals | Patients were instructed to record their pain level using the Visual Analog Scale |
| Inflammatory markers | before treatment, after 3 days and after 7 days | Gingival crevicular fluid samples were collected by periopaper for testing the level of IL-1β and IL-10 |
Countries
Egypt
Contacts
Primary ContactMustafa Sultan
Outcome results
None listed