Alveolar Bone Loss
Conditions
Keywords
Socket preservation, Impacted mandibular third molar, Alveolar ridge Augmentation
Brief summary
This study is designed to evaluate and compare clinically and radiographically the effectiveness of Demineralized Dentin Allograft (DDA) versus Demineralized Dentin Autograft (Auto-DD) for preservation of alveolar ridge dimensions after surgical extraction of the impacted mandibular third molar.
Interventions
PROCEDUREDemineralized Dentin Allograft
20 sockets are randomly allocated to receive the Demineralized Dentin Allograft (split-mouth study)
PROCEDUREDemineralized Dentin Autograft
20 sockets are randomly allocated to receive the Demineralized Dentin Autograft (split-mouth study)
Sponsors
Horus University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Outcomes Assessor)
Intervention model description
20 sockets will be grafted with Demineralized Dentin Allograft (DDA) and 20 sockets will be grafted with Demineralized Dentin Autograft (Auto-DD)
Eligibility
Sex/Gender
ALL
Age
25 Years to 35 Years
Healthy volunteers
Yes
Inclusion criteria
1. Patients aged between 25 to 35 years old. 2. Patients scored as (ASA I). 3. No adverse habits such as smoking, tobacco chewing, alcohol. 4. Patients having bilaterally impacted mandibular third molar with similar degree of difficulty according to (Kim JY, et al). 5. The recipient alveolar sockets are free of any pre-existing periapical pathology, based on x-ray. 6. Alveolar sockets with a depth of 5 mm or more, using periodontal probe for assessment. 7. Patients sign a consent for all procedures.
Exclusion criteria
* 1\) Pregnant or lactating patients. 2) Relevant systemic diseases. 3) Patients with history of chemotherapy or radiotherapy.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Measuring and comparing the height of bone between the two groups | Immediately post-operative, 3months post-operative, 6months post-operative | We will measure the height of the alveolar ridge clinically by using ridge mapping caliper (special caliper forceps used for measuring ridge dimensions) and radiographically on the cone-beam computed tomography (CBCT) and comparing the results of the study group (20 sockets) with the control group (the other 20sockets), to assess the effectiveness of Demineralized Dentin Allograft for ridge preservation |
| Measuring and comparing the width of bone between the two groups | Immediately post-operative, 3months post-operative, 6months post-operative | We will measure the width of the alveolar ridge clinically by using ridge mapping caliper (special caliper forceps used for measuring ridge dimensions) and radiographically on the cone-beam computed tomography (CBCT) and comparing the results of the study group (20 sockets) with the control group (the other 20sockets), to assess the effectiveness of Demineralized Dentin Allograft for ridge preservation |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Assess and comparing the mouth opening of both groups | One day post-operative, one week post-operative | Assess the mouth opening of the patient using a millimeter ruler (by measuring the distance between maxillary incisal edge and mandibular incisal edge) and comparing the results of both groups |
| Assess and comparing the swelling of both groups | One day post-operative, one week post-operative | Swelling levels after surgery will be measured using anatomic landmarks (Tragus-Labial commissure and Tragus-Pogonion), the distances between the landmarks used for the evaluation methods will be measured before the operation. All measurements will be done using millimeter ruler, while the patient will be seated. |
| Assess and comparing the pain of both groups | One day post-operative, one week post-operative | we will use the Visual Analogue Scale (VAS) for pain measurement |
| Assess and comparing the soft tissue parameters (bleeding on probing and color of the gingiva) of both groups | One day post-operative, one week post-operative | The bleeding on probing will be assessed by using periodontal probe and this will be done around mandibular first and second molars |
Countries
Egypt
Contacts
CONTACTMohamed Habib, B.D.S
CONTACTAhmed Khalil, PHD
PRINCIPAL_INVESTIGATORMohamed Habib, B.D.S
Faculty of Dentistry- Horus University in Egypt
STUDY_DIRECTORAhmed Khalil
Faculty of Dentistry- Horus University in Egypt
STUDY_DIRECTOREman Abdelsalam
Faculty of Dentistry- Horus University in Egypt
Outcome results
None listed