Diabetic Retinopathy, DR
Conditions
Brief summary
the aim of this study is to assess the impact of duration of DM on OCTA parameters in diabetic patients without clinical Diabetic retinopathy.
Interventions
DIAGNOSTIC_TESToptical coherence tomography angiography
A non-invasive eye imaging technique that creates high-resolution, 3D maps of blood flow in the retina and choroid by comparing sequential OCT scans to detect the motion of red blood cells to provide a visual contrast to the static tissue that allows the visualization the retinal microvasculature without needing an injectable dye, unlike traditional angiography.
Sponsors
Sohag University
Study design
Observational model
CASE_CONTROL
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
40 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
1. Type of DM: Type 2. 2. Fundus examination: no macular edema or other signs of clinical retinopathy
Exclusion criteria
1. Ocular history : any history of significant ocular injury or disease that could affect the retinal microvasculature such as retinal vascular occlusion, glaucoma, or vitreo-macular disease, as such conditions have also been noted to show sub-clinical OCTA changes \[13, 14\]. 2. Fundus examination: macular edema or any other signs of clinical retinopathy
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| FAZ metrics | baseline | FAZ area, FAZ perimeter & FAZ flow density |
| Superficial Vessel Density | baseline | foveal, average parafoveal & average perifoveal |
| Deep Vessel Density | baseline | foveal, average parafoveal, average perifoveal |
| SCP thickness | baseline | foveal, average parafoveal & average perifoveal |
| DCP thickness | baseline | foveal, average parafoveal & average perifoveal |
| Sectoral superficial vessel density | baseline | superior parafoveal, inferior parafoveal, nasal parafoveal, temporal parafoveal, superior perifoveal, inferior perifoveal, nasal perifoveal & temporal perifoveal |
| Sectoral deep vessel density | baseline | superior parafoveal, inferior parafoveal, nasal parafoveal, temporal parafoveal, superior perifoveal, inferior perifoveal, nasal perifoveal & temporal perifoveal |
Countries
Egypt
Outcome results
None listed