How to Predict Post-Surgical Bleeding and Hemoglobin in Liposuction?

Effect of Using a Mathematical Model Based on pre-and Post-surgical Hemoglobin Differences to Determine the Volume to Aspirate in Primary Body Liposuction.

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT06453772

Enrollment

700

Registered

2024-06-12

Start date

2022-01-01

Completion date

2022-12-01

Last updated

2025-06-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bleeding, Surgery

Keywords

bleeding, abdominoplasty, Liposuction, Hemoglobin

Brief summary

To evaluate the effect of using a mathematical model developed through pre- and post-surgical hemoglobins to predict the volume to aspirate in patients undergoing primary body liposuction.

Detailed description

Postoperative anemia is a significant risk associated with liposuction, yet the scientific literature lacks detailed data on blood loss relative to the volume of fat removed. To address this, the investigators aimed to develop a mathematical formula predicting the decrease in postoperative hemoglobin (Hb post) based on preoperative hemoglobin (Hb pre), Body Mass Index (BMI), and the volume of fat suctioned. An observational, analytical, non-experimental, prospective study was conducted on liposuction patients to validate this predictive formula. Statistical analysis using Spearman's test showed that the results were statistically significant (P \< 0.05).

Interventions

PROCEDURELiposuction

Primary or secondary liposuction is performed by the surgical staff. The study analyzed variables including weight, height, BMI, preoperative hemoglobin, and aspirated volume. Additionally, preoperative hemoglobin (Hb), hematocrit (Hto), platelets, prothrombin time (Tp), partial prothrombin time (TpT), and International Normalized Ratio (INR) were evaluated. Hb and Hto levels were reassessed 24 hours post-surgery to monitor changes.

Study design

Observational model

CASE_ONLY

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

* Patients of indistinct gender, operated on at the Centro Médico Nacional de Occidente for primary liposuction. * Age between 18 to 60 years old * Liposuction technique used: Super wet or Tumescent. * Surgical procedure on any area of the body * Large volume liposuction (\> 5 L) * Use of regional anesthesia

Exclusion criteria

* Presence of any of the following comorbidities: Systemic Arterial Hypertension or Diabetes Mellitus type 2. * Performance of 2 or more procedures * Use of medications (NSAIDs and/or coadjuvants that modify coagulation times).

Design outcomes

Primary

Measure	Time frame	Description
Bleeding Predicting Method	12 months	Mathematical model based on pre-and post-surgical hemoglobins to further predict estimated bleeding

Countries

Mexico

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026