Pes Anserine Bursitis, PRP Injection, Steroid Injection
Conditions
Keywords
Pes Anserine Bursitis, Steroid Injection, PRP injection
Brief summary
The goal of this research is to study the efficacy of treatment between PRP injection and corticosteroid injection in patients with pes anserinus bursitis. The research question is whether PRP can reduce pain more effectively than corticosteroids. The study is divided into two groups: one group receiving PRP injections and the second group receiving corticosteroid injections. Treatment outcomes will be monitored at four time points: baseline, 4 weeks, 12 weeks, and 24 weeks. The outcomes will be measured using the VAS and WOMAC scores.
Detailed description
Randomization of patient with pes anserinus bursitis at opd od ramathibodi hospital. Objective : to study the efficacy of treatment between PRP injection and corticosteroid injection in patients with pes anserinus bursitis Medhods : A randomized controlled trial , Single blinded Participants : Patients with pes anserinus bursitis Randomization : Randomization will be performed using the software STATA 16.0 (StataCorp, College Station, Texas, USA). A various blocked randomization method Interventions and control : * Experimental groups : PRP injection 4 ml * Control groups : Steroid injection , Triamcinolone acetonide(40mg/ml) 1 ml + 1%Lidocaine without adrenaline 3 ml = 4ml By Orthopedic surgeon with ultrasound guide. Allocation and concealment : A central randomization service will prepare sealed envelopes containing the assigned treatment for each patient. The envelopes will be kept in secure location until Break the concealment at outpatient orthopedics department , Ramathibodi hospital Blinding : Randomized controlled trial study, Single blinded The assessor who will be follow up the patients, will be blinded to the group assignments. Outcome measures: Visual Analogue Scale (VAS) , Womac scores Follow up: at 4 weeks, 12 weeks, and 24 weeks after injection. Statistic analysis: STATA 16.0, StataCorp, College Station, Texas, USA Analysis Demographic data : mean, SD Mean difference in patient-relevant outcomes : Independent T- test
Interventions
DRUGPRP injection
Receive pes anserinus PRP injection
DRUGcorticosteroid injection
Receive pes anserinus corticosteroid injection
Sponsors
Ramathibodi Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
TRIPLE (Subject, Caregiver, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Over 18 years old * Patients diagnosed with Pes Anserine Pain Syndrome * Patients willing to participate in the research project by signing a consent form
Exclusion criteria
* Patients with a localized knee infection or a disseminated infection within the past 3 months * Patients with thyroid disorders, rheumatoid arthritis, or other types of knee arthritis * Patients with abnormal blood coagulation or thrombocytopenia * Patients who are pregnant * Patients with any type of cancer * Patients who cannot follow up with treatment until the end of the project * Patients who are unwilling to participate in the project or wish to withdraw from the research project
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Visual analogue scale (VAS) | 6 months | Pain relief outcome : Visual analogue scale (VAS) scale 0(minimum pain) to 10(maximum pain) |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| WOMAC score | 6 months | Functional outcomes : The Western Ontario and McMaster Universities Arthritis Index(WOMAC) version 3.01 Thai version |
Contacts
Primary ContactThaned ekthanaporn
Backup ContactChavarat Jarungvittayakon, Assistant professor
Outcome results
None listed