Acute Myocardial Infarction, Hemorrhagic Myocardial Infarction, Myocardial Hemorrhage, Myocardial Reperfusion Injury, Myocardial Rupture (Post Infarct), Myocardial Stunning
Conditions
Brief summary
Hemorrhagic Myocardial infarctions are at high risk for mechanical complications including cardiac rupture. Prediction of vulnerable myocardial segments is an important step for the stratification of hemorrhagic MI patients. Wall motion index ratio is an important parameter to determine regions of high vulnerability within the 17-segment LV model of hemorrhagic MI.
Interventions
None listed
Sponsors
Rohan Dharmakumar
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 79 Years
Healthy volunteers
No
Inclusion criteria
* Index STEMI * Primary PCI * Able to complete Cardiac MR - STRAIN Protocol
Exclusion criteria
* Contraindication to CMR (Contrast Hypersensitivity, Metallic Implants, Abnormal Rhythms, breathing difficulties)
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Wall Strain Index for Potential Detection of Intramyocardial Hemorrhage | 48 hours Post-PCI | Difference in Wall Strain Index values between patients with intramyocardial hemorrhage and those without, confirmed by cardiac MRI. |
| Wall Strain Index in Detecting the Severity of Intramyocardial Hemorrhage | 48 hours Post-PCI | Relationship between initial Wall Strain Index measurements and the volume of intramyocardial hemorrhage quantified by cardiac MRI |
| Wall Strain Index Ratio in Identification of Vulnerable LV Segments for Cardiac Rupture | 48 hours Post-PCI | Wall Strain Index Ratio for circumferential and longitudinal strain in identifying vulnerable hemorrhagic left ventricular segments at risk for rupture |
Countries
United States
Outcome results
None listed