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Effect of Soleus Muscle Push Ups on Oxidative Stress and Inflammatory Markers, Soleus Endurance, and Adipocytokines Between Type 2 Diabetic, Overweight/Obese and Normal Weight Individuals.

Effect of Soleus Muscle Push Ups on Oxidative Stress and Inflammatory Markers, Soleus Endurance, and Adipocytokines Between Type 2 Diabetic, Overweight/Obese and Normal Weight Individuals.

Status
Not yet recruiting
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT06450847
Enrollment
72
Registered
2024-06-10
Start date
2024-06-30
Completion date
2024-10-31
Last updated
2024-06-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Diabete Type 2, Obesity, Overweight

Brief summary

The study aims to investigate the impact of Soleus Push Ups (SPU) on Soleus Muscle endurance, Oxidative Stress Markers, Inflammatory markers and Adipocytokines among people in the United Arab Emirates. This will be a pre-post intervention study with participants divided into three groups: Lean normal metabolic profile, metabolically healthy overweight/obese, and patients with Type 2 Diabetes Mellitus. Assessment of anthropometry and body composition, Soleus Muscle Endurance, blood tests for Inflammatory Markers, Oxidative Stress Markers, and Adipocytokines will be conducted pre and post-intervention.

Interventions

OTHERSoleus Muscle Push Up Exercise

Members will be asked to do the SPUs for 270 minutes/day for most days of the week (minimum 5 days) for 3 months: 1. Begin seated on a bench or chair so knees form a 90-degree angle with feet flat on the floor and toes pointed forward. Keep spine straight and shoulders back (not hunched or rounded forward). 2. Using a slow and controlled tempo, push toes into the floor and lift heels off the ground. 3. Hold for one to two seconds, pushing down on the balls of feet. Keep your thigh muscles relaxed. 4. Slowly lower heels and return to start. That's 1 rep. Without shoes Educational session will be given before the intervention time WhatsApp messages will be sent 1-2 times/day to remind the participants to continue doing the exercise and ascertain compliance. Also, the participants are required to daily fill logbook about the duration (in minutes) of the SPU that they did.

OTHEROther Exercise

Participants will be asked to continue their regular lifestyle

Sponsors

University of Sharjah
Lead SponsorOTHER

Study design

Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
20 Years to 50 Years
Healthy volunteers
Yes

Inclusion criteria

* Residents of UAE, both males and females * Ages 20-50 years * Uncomplicated Type 2 Diabetic on meds, * Normal lean BMI * Overweight and Obese

Exclusion criteria

* Recent orthopedic surgery in the LLs * Pain in the LLs starting from Hips to Ankle. * Presence of Varicose Veins in the LLs * Present History of any cardiovascular condition * Pregnant females * Morbid Obesity * Diabetics undergoing Insulin therapy only * Smokers and alcohol consumption

Design outcomes

Primary

MeasureTime frameDescription
Adipocytokine levels in the blood3 monthsMeasured in μg/ml, using blood test by specialized personnel

Secondary

MeasureTime frameDescription
Soleus Muscle endurance through Heel Raise Test. • Inflammatory and Oxidative Stress markers through blood sample.3 monthsMeasured as a number, in repetitions. Detailed procedure described previously.

Other

MeasureTime frameDescription
BMI3 monthskg/m2
Anthropometric data including weight, height and fat percentage3 monthsMeasured in kgs, cms and % respectively
Physical Activity and Food habits3 monthsQuestionnaire (International Physical Activity Questionnaire and Food Frequency Questionnaire)
Venous blood specimens3 monthsMeasured in mL, using blood test by specialized personnel

Contacts

Primary ContactAmenah Abdelazim, BPT
aabdelazim@sharjah.ac.ae+971554590707
Backup ContactKalyana Reddy, PhD
kreddy@sharjah.ac.ae+971503614889

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026