Allogeneic Transplantation
Conditions
Brief summary
To look at the effect of a recipient's ancestry and socio-economic status on their choice of bone marrow transplantation donor cells and their chance of receiving genetically similar (allogeneic) bone marrow cells versus cells that are not genetically similar (allograft).
Detailed description
Primary Objectives To prospectively evaluate graft options and choice of donor by patient ancestry and SES for allograft candidates at MDACC. Secondary Objectives * To prospectively evaluate time to transplant for allograft candidates at MDACC. * To evaluate treatment-related mortality for allograft candidates at MDACC. * To assess overall survival for allograft candidates at MDACC. * To prospectively evaluate receipt of preferred unrelated donor for allograft recipients at MDACC. * To evaluate receipt of an optimal graft for allograft recipients at MDACC.
Interventions
BEHAVIORALPatient Ancestry Questionnaires
Participants will be asked to complete a demographics and ancestry questionnaire at the baseline visit before you and your doctor select bone marrow donation candidates.
Sponsors
M.D. Anderson Cancer Center
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
1. ≥ 18 years of age. 2. Candidate for allogeneic transplantation
Exclusion criteria
1\) Allogeneic stem cell transplantation not medically indicated.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Patient Ancestry Questionnaire | Through study completion; an average of 1 year. |
Countries
United States
Contacts
CONTACTWarren Fingrut, MD
PRINCIPAL_INVESTIGATORWarren Fingrut, MD
M.D. Anderson Cancer Center
Outcome results
None listed