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Minerals Status in Relation to Overweight and Obese Adolescent

Effect of Body Composition on Some Blood Minerals Status in Obese and Overweight Adolescent; Cross Sectional Study

Status
Not yet recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06448858
Enrollment
84
Registered
2024-06-07
Start date
2024-06-30
Completion date
2025-06-30
Last updated
2024-06-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Mineral Deficiency

Brief summary

Evaluation of the concentration of serum Mn, Se, iron, Cu & Zn levels in obese and overweight adolescents, Correlate the body composition parameters with these minerals' concentration, Study the association between the metabolic risk factors and the disturbance in minerals levels in these patients.

Detailed description

Obesity in the population tends to be a notable public health threat on the global scale . individuals with higher body mass index (BMI) are considered to have a lower life expectancy . Among the obesity-related indicators, visceral adipose tissue (VAT) is acknowledged an emerging and sensitive predictor for the risk of metabolic syndrome and cardiovascular disease . Therefore, adverse VAT accumulation can influence metabolic health in the population, and its related risk factors should be further investigated. Micronutrients in obese people are explored because of an excess energy consumption, and therefore, an inadequate intake of trace elements and minerals. This imbalance among energy consumption and the intake is known as hidden hunger. Obesity can lead to nutritional metabolic disorders, in which the general state of trace elements and minerals are altered. Only a few studies on child and adolescents obesity concerned Trace Elements (TE). TE is involved in the pathogenesis of obesity and obesity related diseases. We tried to assess trace elements status \[ Manganese (Mn), selenium (Se) copper (Cu),zinc (Zn)\] in obese children and their relationships with VAT and metabolic risk factors of obesity. Manganese (Mn) is an essential trace element . It plays an important role in fat metabolism. Selenium (Se) is an essential micronutrient that acts as an antioxidant and possesses multiple metabolic properties. Copper (Cu) is a trace element that is vital. Cu has been reported to play a role in fat metabolism. Zinc (Zn) plays an important role. Its deficiency impairs growth, metabolism and immunity. Iron (Fe) is an essential trace element to sustain all forms of life. Existing research indicates iron deficiency is one of the comorbidities associated with obesity .

Interventions

DIAGNOSTIC_TESTserum Mn, Se, iron, Cu & Zn levels

Evaluate the concentration of serum Mn, Se, iron, Cu & Zn levels in obese and overweight adolescents.

Sponsors

Assiut University
Lead SponsorOTHER

Study design

Observational model
CASE_CONTROL
Time perspective
CROSS_SECTIONAL

Eligibility

Sex/Gender
ALL
Age
12 Years to 18 Years

Inclusion criteria

1. Patients in adolescent age (12-18 years old) 2. Patients with BMI over 25.

Exclusion criteria

1. Patients younger than 12 years old or older than 18 years old. 2. Patients with history of chronic use of mineral and /or vitamin supplements . 3. Patients with syndromal obesity , endocrine disorder and history of any chronic diseases , 4. Patients under special diets or chronic use of medication .

Design outcomes

Primary

MeasureTime frameDescription
Concentration of serum Zinc1 yearEvaluate the concentration of serum Zn levels in obese and overweight adolescents.
concentration of serum Manganese1 yearEvaluate the concentration of serum Mn levels in obese and overweight adolescents.
Concentration of serum selenium1 yearEvaluate the concentration of serum Se levels in obese and overweight adolescents.
Concentration of serum Iron1 yearEvaluate the concentration of serum Iron levels in obese and overweight adolescents.
Concentration of serum copper1 yearEvaluate the concentration of serum Cu levels in obese and overweight adolescents.

Secondary

MeasureTime frameDescription
Visceral fat and it's relation to mineral levels1 yearCorrelate Visceral fat with these minerals' concentration.
Basal metabolic rate and it's relation to mineral levels1 yearCorrelate basal metabolic rate with these minerals' concentration.
Body fat percentage and it's relation to mineral level1 yearCorrelate body fat percentage with these minerals' concentration.
BMI and its relation to mineral levels1 yearCorrelate the BMI with these minerals' concentration.

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026