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Epidemiological Study of Out-of-hospital Cardiac Arrest in Guangzhou

Epidemiological Study of Out-of-hospital Cardiac Arrest in Guangzhou

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06448156
Enrollment
44375
Registered
2024-06-07
Start date
2021-01-01
Completion date
2025-12-31
Last updated
2024-06-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cardiac Arrest, Sudden Cardiac Death

Brief summary

Aim This was a population-based retrospective cohort study of OHCA. This study intends to retrospectively analyze the data of pre-hospital emergency system in Guangzhou for 10 years, explore the incidence trend of OHCA in Guangzhou for 10 years; Through further analysis, we try to explore the time distribution characteristics of OHCA in order to understand the epidemiological characteristics and rules of OHCA in super large cities in southern China. Methods The pre-hospital traffic data in the main urban area of Guangzhou Emergency Medical Command Center database from 2011 to 2020 were collected. The cases diagnosed as cardiac arrest and sudden death were screened, and the cases with non-cardiac causes in the diagnosis were deleted. The crude incidence rate and age-standardized incidence rate of OHCA were calculated. Joinpoint software was used to calculate the changing nodes in the OHCA incidence trend, and the AnnualPercent Change (APC) and Average AnnualPercent Change (Average AnnualPercent Change, APC) of OHCA incidence were calculated. AAPC). The OHCA data were grouped according to the six main urban areas, and the crude incidence rate, ASIR and changing trend of the six main urban areas were calculated. The data of OHCA were grouped by age, and the crude incidence rate, ASIR and changing trend of each age group were calculated. The data information was divided into groups according to 24 hours a day, 7 days a week, and four seasons. The number of OHCA cases in different time periods was statistically described. The data were imported into SPSS 26.0 for analysis, and Mann-Kendall test was used to evaluate the statistical significance of the time trend. Time rhythm variability was tested for mean distribution using chi-square goodness of fit test.

Interventions

DIAGNOSTIC_TESTcardiac arrest and sudden death

Selection of cases with a secondary diagnosis containing the diagnostic keywords cardiac arrest and sudden death.cardiac arrest and sudden death.The incidence rate is then calculated

Sponsors

Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
0 Years to 120 Years
Healthy volunteers
No

Inclusion criteria

Cases in the database with a secondary diagnosis containing the diagnostic keywords cardiac arrest and sudden death

Exclusion criteria

1. cases where the diagnosis of cardiac arrest and sudden death includes a diagnosis of a non-cardiac cause such as asphyxiation, suicide, drowning, advanced cancer, trauma, shock, poisoning, cerebral vascular accident, etc; 2. cases with duplicate records of sex, age, time of call, pick-up address and initial diagnosis

Design outcomes

Primary

MeasureTime frameDescription
Crude incidence rate2011-01-01 to 2020-12-31The frequency of new cases of a disease in a given population over a given period of time.
Age standardized incidence rate2011-01-01 to 2020-12-31Incidence rates after removing the influence of age, and incidence rates normalised by age. The rationale is that age is an important influence on cancer incidence, with higher incidence rates occurring at older ages, so that if the age structure of the population in two regions is very different, it is not possible to determine whether the high incidence of a disease in a particular region is due to a different age composition or to other influences if incidence rate comparisons are applied.
Average annual percentage change2011-01-01 to 2020-12-31Calculated using the weighted average of the APC, it is an overall measure of trend.
Annual percentage change2011-01-01 to 2020-12-31Indicates the change from one year to the next within a segment at a constant percentage on a log-linear model for evaluating trends within segments.

Countries

China

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026