The Feasibility of a Radiological Score Based on CT Signs for Recognizing Salvageable Bowel in Acute Mesenteric Ischemia

The Feasibility of a Radiological Score Based on Quantified Analysis of Computed Tomography Signs for Recognizing Salvageable Bowel in Acute Mesenteric Ischemia: A Retrospective Analysis of Prospective Study

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT06445660

Acronym

AMESIradiol

Enrollment

200

Registered

2024-06-06

Start date

2022-06-06

Completion date

2025-05-31

Last updated

2025-03-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Mesenteric Ischemia

Brief summary

Computed tomography (CT) is the standard modality for scanning patients with critical acute abdominal conditions, including suspected acute mesenteric ischemia (AMI). CT imaging can potentially differentiate between reversible and irreversible ischaemic damage of the bowel. This moment is pivotal in selecting the treatment strategy for AMI - in the absence of irreversible damage; reperfusion therapy can preserve intestinal viability, thereby avoiding the need for bowel resection. The present study tests the hypothesis that combining several symptoms may enhance the diagnostic performance of CT scanning in detecting salvageable bowel in patients with AMI. This study is an ancillary component of the AMESI study (Clinical Trials: NCT05218863) - a prospective, multicentre observational study aimed at identifying the incidence and describing the outcomes of acute mesenteric ischemia (AMI) in adult hospitalized patients. The ultimate purpose of the present study is to create a computed tomography-based radiological score for the assessment of bowel viability in patients with AMI.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Participant in AMESI study * confirmed or suspected acute mesenteric ischaemia * CT scan of the entire abdominal cavity / full body using intravenous contrast media is available

Exclusion criteria

* Scans without the use of an intravenous contrast media or those covering only a partial area of the abdomen will be excluded.

Design outcomes

Primary

Measure	Time frame	Description
Frequency rate	up to one month	Frequency rate of common radiological signs in AMI patients with and without salvageable bowel.

Secondary

Measure	Time frame	Description
Performance of the radiological score	up to one month	Performance of the radiological score in patients with different types of AMI.

Countries

Estonia

Contacts

Primary ContactJoel Starkopf

joel.starkopf@ut.ee53318400

Backup ContactKätlin Eiche

Katlin.Eiche@ut.ee

Outcome results