Hypoparathyroidism, Pseudo Hypoparathyroidism
Conditions
Keywords
Hypoparathyroidism, Pseudo Hypoparathyroidism, Clinical Registry, Endocrinology, Parathyroid gland
Brief summary
Observational, multicenter, national, cross-sectional study aiming to describe the epidemiological clinical, biological and therapeutic profile of patients suffering from defect in secretion (hypoparathyroidism) or action (pseudo-hypoparathyroidism) of parathyroid hormone.
Detailed description
Endocrinologists from both sectors (public and private) are participating in the study. Data will be captured electronically by DACIMA Clinical Suite, according to FDA 21 CFR part 11 (Food and Drug Administration 21 Code of Federal Regulations part 11), HIPAA (Health Insurance Portability and Accountability Act) & ICH (International Conference on Harmonisation) requirements.
Interventions
None listed
Sponsors
Société Tunisienne D'endocrinologie De Diabétologie Et Des Maladies Métaboliques
Dacima Consulting
Study design
Observational model
COHORT
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Healthy volunteers
No
Inclusion criteria
* Hypoparathyroidism defined by low serum calcium \< 2.2 mmol/l (\< 88 mg/l) associated with inadequate PTH (low or normal) and normal creatinine
Exclusion criteria
* Cervical surgery \< 6 months. * Transient (neonatal, etc.) or functional (dysmagnesemia, etc.) hypoparathyroidism. * Other causes of hypocalcemia: vitamin D deficiency, chronic renal failure, etc. * Familial hypocalcemia hypercalciuria. * Pseudo-pseudo-hypoparathyroidism.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Incidence of primary hypoparathyroidism | Day 1 | Number of subjects with primary hypoparathyroidism at enrollment |
| Incidence of congenital hypoparathyroidism | Day 1 | Number of subjects with congenital hypoparathyroidism at enrollment |
| Incidence of acquired hypoparathyroidism | Day 1 | Number of subjects with acquired hypoparathyroidism at enrollment |
| Incidence of secondary hypoparathyroidism | Day 1 | Number of subjects with secondary hypoparathyroidism at enrollment |
Countries
Tunisia
Contacts
Primary ContactNabila Rekik Mejdoub, MD
Backup ContactRabie Razgallah, MD
Outcome results
None listed