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SUPPLEMENTARY EFFECTS OF RESISTANCE TRAINING IN ADDITION TO JOINT MOBILIZATION IN PERSONS WITH KNEE OSTEOARTHRITIS

SUPPLEMENTARY EFFECTS OF RESISTANCE TRAINING IN ADDITION TO JOINT MOBILIZATION IN PERSONS WITH KNEE OSTEOARTHRITIS

Status
Enrolling by invitation
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT06444932
Enrollment
44
Registered
2024-06-06
Start date
2024-06-10
Completion date
2024-12-30
Last updated
2024-06-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Knee Osteoarthritis

Brief summary

Joint mobilization and resistance exercise training are effective conservative treatment options for the management of osteoarthritis. However, currently no study has highlighted the supplementary effects of resistance training in addition to joint mobilization in people suffering from knee osteoarthritis. The current study is aimed at bridging the gap in literature and providing evidence regarding the additive impact of resistance training to joint mobilization in knee osteoarthritis.

Interventions

Patellofemoral and tibiofemoral joint mobilization

PROCEDUREResistance Exercise Training

Lower limb resistance exercise training

Transcutaneous Electric Nerve Stimulation (TENS)

Heating pad for heat therapy

Sponsors

Foundation University Islamabad
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Investigator)

Intervention model description

Double arm parallel design RCT

Eligibility

Sex/Gender
ALL
Age
40 Years to 70 Years
Healthy volunteers
No

Inclusion criteria

* Knee OA grade I-III * Individuals of either gender aged 40-70 years * Knee OA history of no less than 3 months * Knee pain no more than 8/10 cm on the visual analogue scale (VAS) * Radiological evidence of grade III or less on Kellgren classification.

Exclusion criteria

* Those with signs of serious pathology such as malignancy, inflammatory disorder or infection. * History of trauma or fractures in lower extremity * Signs of lumbar radiculopathy or myelopathy * History of knee surgery or replacement and/or receiving intra-articular steroid therapy in the preceding two months

Design outcomes

Primary

MeasureTime frameDescription
Walking related performance fatigability4 weeksWalking related performance fatigability will be measured using 6 minute walk test. Greater fatigability indicates poorer outcome.
Stride Length4 weeksGait analysis will be done to analyze stride length. A greater stride length signifies positive outcome and prognosis.
Gait velocity4 weeksGait analysis will be done to analyze gaot velocity. A greater gait velocity signifies positive outcome and prognosis.
Knee Pain4 weeksKnee Pain will be measured using visual analogue scale (VAS) from 0-100mm. A higher score on VAS indicated greater pain.
Knee range of motion4 weeksKnee range of motion will be measured using a goniometer. A higher ROM signifies positive outcome.
Functional Disability4 weeksKnee functional disability will be assessed using Knee Osteoarthritis and Outcome Score (KOOS) with a score ranging from 0-100. A lower score on KOOS signifies greater functional disability.
Isometric Muscle Strength4 weeksIsometric Muscle Strength will be quantified using dynamometer. A higher score on dynamometer signifies greater muscle strength and good prognosis.
Functional capacity4 weeks5 repetition sit to stand test will be used to determine knee related functional capacity, which will be quantified in terms of time. A smaller time will denote greater functional capacity.

Countries

Pakistan

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026