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Clinico-biological Collection of Bone, Calcium and Growth Plate Pathologies

Creation of a Biological Collection to Study the Pathophysiology and Identify Predictive Factors for the Evolution of Bone, Calcium and Growth Plate Pathologies

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06444503
Acronym
OSCAR
Enrollment
350
Registered
2024-06-05
Start date
2024-09-16
Completion date
2034-09-16
Last updated
2026-06-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bone Disorder

Brief summary

The aim of this project is to set up a biological and clinical collection of patients with progressive bone, calcium and growth plate pathologies. This collection will provide a better understanding of the mechanisms involved in growth plate and bone damage in these diseases and identify factors predictive of progression and new therapeutic targets.

Interventions

OTHERBiological samples

Blood and urine will be taken in larger quantity

Surgical residues may be preserved in the event of surgery carried out as part of the treatment.

Sponsors

University Hospital, Toulouse
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
No minimum to 99 Years
Healthy volunteers
No

Inclusion criteria

* Children (from birth) with growth plate or bone pathology * Patients affiliated to or benefiting from a social security scheme * Patients able to receive information about the study and to understand the information form in order to participate in the study. This implies : * mastery of the French language * Not being subject to a restriction of rights by the judicial authorities * Patients or legal representatives having given their consent to participate in the study (expression of non-opposition).

Exclusion criteria

* Patients under legal protection (guardianship, curatorship or safeguard of justice) * Pregnant or breast-feeding women

Design outcomes

Primary

MeasureTime frameDescription
Building a collection of biological samples and clinical-biological data from patients presenting bone, calcium and growth plate pathologiesDay 0 and through study completion, an average of 5 yearsBlood and urine sampling

Secondary

MeasureTime frame
Identification of potential markers of disease progression based on new knowledge.Day 0 and through study completion, an average of 5 years

Countries

France

Contacts

CONTACTThomas EDOUARD, MD
edouard.t@chu-toulouse.fr0534558555
CONTACTSanaa EDDIRY
eddiry.s@chu-toulouse.fr0561776110
PRINCIPAL_INVESTIGATORThomas EDOUARD, MD

University Hospital, Toulouse

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Jun 6, 2026