Bone Disorder
Conditions
Brief summary
The aim of this project is to set up a biological and clinical collection of patients with progressive bone, calcium and growth plate pathologies. This collection will provide a better understanding of the mechanisms involved in growth plate and bone damage in these diseases and identify factors predictive of progression and new therapeutic targets.
Interventions
Blood and urine will be taken in larger quantity
Surgical residues may be preserved in the event of surgery carried out as part of the treatment.
Sponsors
Study design
Eligibility
Inclusion criteria
* Children (from birth) with growth plate or bone pathology * Patients affiliated to or benefiting from a social security scheme * Patients able to receive information about the study and to understand the information form in order to participate in the study. This implies : * mastery of the French language * Not being subject to a restriction of rights by the judicial authorities * Patients or legal representatives having given their consent to participate in the study (expression of non-opposition).
Exclusion criteria
* Patients under legal protection (guardianship, curatorship or safeguard of justice) * Pregnant or breast-feeding women
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Building a collection of biological samples and clinical-biological data from patients presenting bone, calcium and growth plate pathologies | Day 0 and through study completion, an average of 5 years | Blood and urine sampling |
Secondary
| Measure | Time frame |
|---|---|
| Identification of potential markers of disease progression based on new knowledge. | Day 0 and through study completion, an average of 5 years |
Countries
France
Contacts
University Hospital, Toulouse