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New Generation Low Level Laser Effect in Myofacial Pain Syndrome

New Generation Low Level Laser Effect on Masseter Muscle Oxygenation, Bite Force and Algometric Changes in Myofacial Pain Syndrome: A Randomised, Placebo-controlled Clinical Trial

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT06442553
Enrollment
45
Registered
2024-06-04
Start date
2024-01-15
Completion date
2024-04-01
Last updated
2024-06-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Myofascial Pain Syndrome

Keywords

low level laser therapy, myofascial pain syndrome, bite forces, visual analogue scale, gaalas laser, neodymium doped yttrium aluminum garnet lasers

Brief summary

Low level laser treatments have been used to treat painful trigger points in myofascial pain syndrome (MPS), but the effectiveness of the appropriate laser type and parameters is still uncertain. The aim of this study was to compare the effectiveness of different types of low level laser treatment (LLLT) in reducing pain levels, changing oxygen saturation and bite force in patients with MPS.

Detailed description

A total of 45 patients with MPS were randomly divided into three groups. First group received LLLT with GRR laser over massater muscle region. Patients in the second group were treated with Nd:YAG laser and the same protocol with Nd:YAG laser was performed in the placebo group using sham device. Pain was evaluated by visual analogue scale (VAS), change in oxygen concentration in the massater muscle was measured by functional near-infrared spectroscopy- fNIRS and bite force was measured with Flexiforce sensors before and after treatment.

Interventions

DEVICEGRR laser

A total of 15 sessions were applied to each patient for three weeks, five times per week.

A total of 10 sessions, five sessions per week, were applied

Sponsors

University of Gaziantep
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
FACTORIAL
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to 30 Years
Healthy volunteers
Yes

Inclusion criteria

-patients with symptoms of temporomandibular disorders and diagnosed with MPS as a result of the clinical examination.

Exclusion criteria

* Patients with internal TMJ irregularities or degenerative joint changes, * patients with restricted mouth opening, deviation or deflection, * patients with systemic diseases, * pregnant women, * patients who had received MPS treatment within the previous year

Design outcomes

Primary

MeasureTime frameDescription
change from baseline in pain on the 10 point visual analogue scale (VAS) at week 3baseline and week 3Patients were asked to rate the intensity of their pain on a scale from 0 to 10. They were told that a score of 0 meant no pain, a score of 10 meant severe pain and a score of 5 meant moderate pain
change from baseline in oxygen concentration in the massater muscle at week 3baseline and week 3oxygen concentration in the massater muscle was measured by functional near-infrared spectroscopy- fNIRS (ARGES cerebro, Hemosoft Inc., Ankara, Turkey) before and after treatment for each patient.
change from baseline in bite force values at week 3baseline and week 3bite force values were recorded by Flexiforce sensors before and after treatment for each patient.

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 6, 2026