Survivorship
Conditions
Keywords
Adult Cancer Survivors, Anti-Inflammatory Lifestyle for Cancer Survivors
Brief summary
To test the feasibility and acceptability of AILI and associated research procedures among emerging adult cancer survivors (EACS, N=16) age 18-29.
Detailed description
This is a single-arm pilot trial designed to assess the feasibility and acceptability of an anti-inflammatory lifestyle intervention (AILI) for emerging adults (EA) adapted for emerging adult cancer survivors (EACS).
Interventions
BEHAVIORALAnti-Inflammatory Lifestyle Intervention
Content includes training in empirically-supported strategies to improve psychological function (e.g., restructuring negative thoughts, distress tolerance), with a focus on changing discrete behaviors linked to inflammation (e.g., sleep, processed foods, physical activity), all intertwined with evidence-based behavior change content adapted to meet the needs of EACS. Participants will also receive digital tools to facilitate daily self-monitoring (Fitbit activity monitor, wireless scales, self-monitoring app) and generate information for tailored weekly e-coaching
Sponsors
Virginia Commonwealth University
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
SUPPORTIVE_CARE
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 29 Years
Healthy volunteers
No
Inclusion criteria
* Age 18-29 * Cancer diagnosis of any type * Body fat percentage \>16.2% for women; \>10.6% for men
Exclusion criteria
* Individuals receiving active chemotherapy/radiation or those having completed active chemotherapy/radiation within the past 6 months * Individuals who are currently pregnant or lactating * Current involvement in a weight loss program or current use of weight loss medication * Individuals who report any other uncontrolled medical conditions that may pose a safety issue given the recommendations for the diet and unsupervised physical activity (e.g., uncontrolled hypertension) * Individuals with rheumatologic and gastrointestinal conditions associated with severe systemic inflammation (e.g., rheumatoid arthritis, systemic lupus erythematosus, Crohn's disease) * Individuals with medical conditions resulting in known perturbations in the hypothalamic-pituitary-adrenal axis (e.g., endogenous hypercortisolemia \[Cushing's syndrome\] or adrenal insufficiency) * Individuals who report a heart condition, chest pain during periods of activity or rest, or loss of consciousness as assessed by the Physical Activity Readiness Questionnaire (PAR-Q) * Report of lifetime diagnosis of Anorexia Nervosa or Bulimia Nervosa, or any compensatory behaviors (vomiting, laxative abuse) within the previous 3 months * Hospitalization for depression or other psychiatric disorder within the past 12 months * Report of lifetime diagnosis of bipolar disorder or psychotic disorder * Indication of current suicidal intent * Inability to speak and read English
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Test the feasibility of Anti-Inflammatory Lifestyle Intervention (AILI) and associated research procedures among emerging adult cancer survivors (EACS) age 18-29 | Day 0, At end of recruitment period | The percentage of participants that enroll |
| Test the feasibility of AILI and associated research procedures among EACS age 18-29 | 4 months | The percentage of participants that complete the post intervention questionnaire |
| Test the feasibility of Anti-Inflammatory Lifestyle Intervention (AILI) and associated research procedures among EACS age 18-29. | 4 months | The percentage of participants that complete the post intervention blood draw |
| Assess the acceptability of AILI and associated research procedures among EACS age 18-29. | 4 months | The percentage of participants that complete all study sessions |
Outcome results
None listed