Female Pattern Hair Loss, Platelet-rich Fibrin, Platelet-Rich Plasma
Conditions
Keywords
female pattern hair loss, platelet-rich plasma, platelet-rich fibrin
Brief summary
The goal of this clinical trial is to compare between platelet-rich fibrin and platelet-rich plasma in female pattern hair loss . The main question\[s\] it aims to answer are: * efficacy between platelet-rich fibrin and platelet-rich plasma * safety between platelet-rich fibrin and platelet-rich plasma Participants will be divided into 2 side of treatment with composed of 1. Platelet rich plasma 2. Platelet rich fibrin
Detailed description
Subject was treated both platelet-rich fibrin and platelet-rich plasma for 3 times which 1 month interval then will be followed up at 4 months and 6 months after last treatment
Interventions
DEVICEPlatelet rich plasma
Subjects were treated by Platelet rich plasma in each side of head (Left or right)
DEVICEPlatelet rich fibrin
Subjects were treated by Platelet rich fibrin in each side of head (Left or right)
Sponsors
Siriraj Hospital
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE
Intervention model description
All subject were injected with PRP and PRF at baseline, 4 weeks and 8 weeks with split-head of sides of injection.
Eligibility
Sex/Gender
FEMALE
Age
20 Years to 55 Years
Healthy volunteers
No
Inclusion criteria
* Age 20-55 years * Female * Subject who was diagnosed with Female pattern hair loss in Ludwig Classification 2 (part width 2-4 centimeters) by Dermatologist
Exclusion criteria
* Pregnancy or Lactation subjects * Subject with history of platelet dysfunction, low platelet, anemia, cirrhosis, cancer, or immunocompromised host * Subject who are active smoking and alcoholism * Subject who has dermatitis, scar or infection at intervention area * Subject who has history of allergy to anesthesia drug * Subject who taking NSAIDs, Hormonal drug, anticoagulants drug * Subject who has psychiatric condition diagnosed by psychiatrist * Subject who are not allowed to take a photo
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Trichoscan | baseline(week0), 4 months after last treatment(week20), 6 months after last treatment(week28) | Average counts and density of hair per 1.5mm\^2 |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| The 7-point of doctor subjective global assessment | baseline(week0),1 month after first treatment(week4), 1 months after second treatment(week8), 4 months after last treatment(week20), 6 months after last treatment(week28) | Evaluation of improvement through picture by doctor |
| The 7-point of patient subjective global assessment | baseline(week0),1 month after first treatment(week4), 1 months after second treatment(week8), 4 months after last treatment(week20), 6 months after last treatment(week28) | Evaluation of improvement through picture by patient |
| Visual analog scale | baseline(week0), 1 month after first treatment(week4), 1 months after second treatment(week8) | pain during intervention |
Countries
Thailand
Contacts
Primary ContactRattapon Thuangtong, Asst. Prof.
Backup ContactNoldtawat Viriyaskultorn, MD
Outcome results
None listed