Cancer, Depressive Symptoms, Sedentary Behavior, Survivorship
Conditions
Brief summary
The goal of this observational study is to evaluate the joint prognostic effects of physical function and mental health on survival of cancer survivors.
Detailed description
Cancer survivors were selected from the National Health and Nutrition Examination Survey (NHANES) between 2007 and 2018. Total sedentary time was assessed by self-reported daily hours of sitting and depressive symptoms were assessed by Patient Health Questionnaire 9 (PHQ-9). Kaplan-Meier (KM) curves and the Cox regression analyses were used to evaluate the separate and joint prognostic effects of sedentary behavior and depressive symptoms with mortality outcomes of cancer survivors.
Interventions
BEHAVIORALSedentary behavior
Total sedentary time was assessed by self-reported daily hours of sitting
BEHAVIORALDepressive symptoms
depressive symptoms were assessed by Patient Health Questionnaire 9 scale
Sponsors
West China Hospital
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* Adults with aged above 18 year old
Exclusion criteria
* Without a history of cancers * Without records of sedentary behavior or depressive symptoms test * Incomplete follow-up information
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| All-cause mortality of cancer survivors | Jan 1, 2007 to 31 Dec, 2019 | Joint association between sedentary behavior and depressive symptoms with all-cause mortality of cancer survivors |
| Cancer mortality of cancer survivors | Jan 1, 2007 to 31 Dec, 2019 | Joint association between sedentary behavior and depressive symptoms with cancer mortality of cancer survivors |
| Non-cancer mortality of cancer survivors | Jan 1, 2007 to 31 Dec, 2019 | Joint association between sedentary behavior and depressive symptoms with non-cancer mortality of cancer survivors |
Outcome results
None listed