Bone Regeneration
Conditions
Brief summary
The aim of this study is to evaluate osseous regeneration efficacy of bentonite gel with hydroxyapatite in comparison with hydroxyapatite incase of intrabony defects The test group includes patients with intrabony defects where flap surgery is will be performed and bentonite clay gel with HA will be placed and in control group only HA is placed.
Detailed description
Experimental: Main treatment group bentonite with hydroxyaatite is added into the defect site. Comparator: In patients allocated to control group,only hydroxyapatite is added.
Interventions
OTHERbentonite clay gel with hydroxyapatite
bentonite clay gel presents great potential for bone healing and it leads to the formation of interconnected microporous structure, which can promote native cell infiltration, proliferation,
Sponsors
Dr R Viswa Chandra
Study design
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
1. Systemically healthy male and female patients of age \>18 years 2. two-walled or three-walled intrabony defects and 3. probing pocket depths (PPD) of ≥ 5mm.
Exclusion criteria
1. Medically compromised patients, 2. patients \<18 years of age, 3. pregnant women, 4. heavy smokers, and 5. patients who underwent radiotherapy or chemotherapy are excluded.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| RVG | baseline , 3months,6months | 1\. Radiovisiography will be used to assess bone regeneration achieved post operatively after 3 months and 6 months. |
| probing depth | baseline , 3months,6months | 2\. Assessment of probing depth using probe at baseline and postoperatively at 3 and 6 months |
| clinical attachment level | baseline , 3months,6months | Assessment of clinical attachment level using probe at baseline and post operatively at 3 and 6 months. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| 1. Assessment of plaque - according to Turesky modification of Quigley and Hein Plaque Index, 1970. 2. Assessment of Gingivitis - according to Loe H and Silness P, 1963. | baseline ,3months,6months | 1. Assessment of plaque - according to Turesky modification of Quigley and Hein Plaque Index, 1970. 2. Assessment of Gingivitis - according to Loe H and Silness P, 1963. |
Countries
India
Contacts
Primary ContactDr.viswa chandra MDS
Outcome results
None listed