Pulpitis - Irreversible
Conditions
Brief summary
Clinical and radiographic assessment of A-prf,A-prf combined with nanochitosan compared to chitosan for symptomatic irreversible pulpits in lower permanent first molar
Detailed description
3 groups are allocated using : Aprf Aprf combined with nanochitosan Chitosan Each group will be subjected to tests: Tooth sensibility via EPT (electrical pulp tester)and thermal test Radiolucency in digital radiograph Pain in NRS(6-12-24-72h)for 1 week
Interventions
PROCEDUREPULPOTOMY OF MATURE PERMENANT TEETH
Removal of coronal pulp and expose the orifices to apply the materials with aim to preserve vitality of remaining pulp
Sponsors
Future University in Egypt
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Intervention model description
Intervention: Intervention 1 : Vital pulp therapy using A-PRF as capping material. Intervention 2 : Vital pulp therapy using A-PRF mixed with Nano-Chitosan as capping material. Control/Comparator: Vital pulp therapy using Chitosan as capping material.
Eligibility
Sex/Gender
ALL
Age
15 Years to 30 Years
Healthy volunteers
Yes
Inclusion criteria
* Patients suffering from Symptomatic irreversible pulpitis in mature mandibular molars only will be involved. * Patients of either gender aged from 15-30. * Tooth should give positive response to cold test. * Haemostasias should be achieved after total pulpotomy. * The tooth is restorable and free from advanced periodontal disease, cracks and splits. * Patients should be free from any systemic disease that may affect normal healing and predictable outcome. * Patients who will agree to the consent and will commit to follow-up period. * Patients with mature root. * Patients with no internal or external resorption and no periapical lesions. * Soft tissues around the tooth are normal with no swelling or sinus tract.
Exclusion criteria
* Patients with immature roots. * Haemostasias after 10 minutes can not be controlled after total pulpotomy * Patients with any systemic disease that may affect normal healing. * Patients with periapical lesions or infections. * Pregnant females. * Patients who could/would not participate in a 6 months follow-up. * Patients with fistula or swelling * Patients with necrotic pulp. * Patients with old age.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| pain assessment | 6,12,24,72hours and 7 days postoperative | Pain assessment using numerical rate scale |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Clinical and radiographic success | 1,3,6,9and 12 months | It includes clinical and radiographic success if either of them failed the case will considered failed. Clinical failure :signs and symptoms of inflammation or infection Radiograph success and failure based on periapical index |
Countries
Egypt
Contacts
Primary Contactmai S abdelwahed, Bachelor
Backup ContactHala s abdelwahed, student
Outcome results
None listed