Bowel Preparation, Colonoscopy
Conditions
Keywords
Bowel preparation for colonoscopy
Brief summary
We have developed a novel inadequate bowel preparation prediction model based on a systematic review and meta-analysis. The goal of this multicenter observational study is to validate the accuracy of this model.
Detailed description
The primary outcome is quality of bowel preparation. The secondary outcomes include polyp/adenoma detection rate, willingness of undergoing colonoscopy again and adverse events.
Interventions
PROCEDUREBowel preparation before colonoscopy
Patients use purgative for bowel cleansing before colonoscopy.
Sponsors
General Hospital of Shenyang Military Region
Study design
Observational model
COHORT
Time perspective
OTHER
Eligibility
Sex/Gender
ALL
Age
18 Years to 94 Years
Healthy volunteers
Yes
Inclusion criteria
1. adult patients (age is ≥18 years old); 2. patients undergoing colonoscopy; 3. written informed consent.
Exclusion criteria
1. patients undergoing emergent colonoscopy; 2. patients with major psychiatric disorders; 3. pregnant or breast feeding patients; 4. patients with contraindications for colonoscopy (e.g., heart failure, renal insufficiency); 5. patients suspected to have intestinal obstruction, stenosis or perforation; 6. poor compliance with the bowel preparation protocol (poor compliance is indicated if the dose of medication was \< 75% of the prescribed dose; 7. incomplete colonoscopy because of other circumstances apart from inadequate cleansing 8. patients previously enrolled in this study.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Quality of bowel preparation | During the procedure of colonoscopy | A total BBPS score ≥6 with BBPS score ≥2 for each colon segment was considered to have adequate bowel preparation. Each segment of the colon is scored from 0 to 3, with higher scores indicating superior cleansing, and summed for a total score that can range from 0 to 9. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Adenoma and/or polyp detection rate | During the procedure of colonoscopy | Proportion of patients with at least one adenoma and/or polyp detected during colonoscopy |
| Number of polyps and/or adenomas | During the procedure of colonoscopy | Number of polyps and/or adenomas detected during colonoscopy |
| Adverse events | Before the procedure of colonoscopy | Incidence of abdominal pain, bloating, nausea/vomiting after intake of purgative. |
Countries
China
Outcome results
None listed