Colorectal Cancer
Conditions
Keywords
Obstruction, Bridge To Surgery
Brief summary
The aim of this observational study is to determine effect of stent placement on survival results in first three years in a patient who applied to the emergency department with obstruction due to colorectal cancer. Eligible patients divided into two groups. Group A includes patients underwent emergency surgery directly. Patients underwent elective surgery following stent placement as bridge-to-surgery. Patients underwent elective surgery following bridge-to-surgery stent placement were accepted as Group B.
Detailed description
Patients who applied to emergency department of a single tertiary referral center between January 2016 and December 2020 and diagnosed as left sided obstructive colorectal cancer were included in this retrospective study. All patients were equal or older than 18 years and histopathologically found to have primary colorectal malignant neoplasms. Patients were excluded from the analysis if they met any of the following criteria: * Who underwent emergency surgery due to unsuccessful stent application intervention or stent-related complications developed, * Those with middle and lower rectum tumors or received neoadjuvant treatment, * Perforation, * Who underwent subtotal or total colectomy (as a result of colon ischemia in the cecum, microperforation, etc.), * Recurrent disease patients * Patients have metastasis
Interventions
PROCEDURESelf-Expandable Metallic Stent Placement
Sponsors
Yasir Musa Kesgin, MD
Study design
Observational model
CASE_CONTROL
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* All patients were equal or older than 18 years and histopathologically found to have primary colorectal malignant neoplasms and diagnosed as left sided (descending colon, sigmoid colon and upper rectum) obstructive colorectal cancer were included
Exclusion criteria
* Who underwent emergency surgery due to unsuccessful stent placement intervention * Who underwent emergency surgery due to stent-related complications * Those with middle and lower rectum tumors * Those received neoadjuvant treatment, * Patients have perforation, * Who underwent subtotal or total colectomy (as a result of colon ischemia in the cecum, microperforation, etc.), * Who has a recurrent disease or metastasis.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Overall Survival | 3 years | The survival time of patient after being diagnosed as colorectal cancer after coming to emergency department |
| Disease Free Survival | 3 years | The local or systemic recurrence free time period of patient after being diagnosed as colorectal cancer after coming to emergency department |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Mortality | 90 days | Death of patient in postoperative first three months |
| Serious complications | 90 days | Postoperative complications of patients that have a Clavien-Dindo Score greater than or equal to 3 |
| Minimally invasive surgery | 90 days | Patients that found a chance for fully minimally invasive surgery for resection of colorectal cancer |
| End colostomy rate | 90 days | Patients that have a end colostomy at the end of surgical resection of colorectal cancer |
Outcome results
None listed