Cataract, Macular Edema
Conditions
Keywords
OCTA;RPC; IGS;PCME
Brief summary
Pseudophakic cystoid macular edema (PCME), also known as Irvine-Gass syndrome (IGS), is an accumulation of fluid in the macula that occurs after cataract surgery, with an early or late presentation (cut-off 3 months) . It is the most common cause of decreased vision after uneventful phacoemulsification, with a rare incidence of 0.1-2.35% for clinically significant PCME . Macular edema in IGS can be diagnosed and classified by optical coherence tomography (OCT), which enables its morphologic assessment. Fluorescein angiography (FA) is the gold standard to perform differential diagnosis for macular edema. To date, OCT angiography (OCTA) has been proposed to study various retinal vascular diseases. In contrast to FA, OCTA is able to visualize Radial peripapillary vessel density (RCP). The aim of this study was to investigate abnormalities in the vascular network of the optic nerve head in patients with IGS compared to healthy eyes, using OCT-A
Interventions
DIAGNOSTIC_TESTOCTA
OCTA is a non invasive diagnostic technique to visualize RPC
Sponsors
Federico II University
Study design
Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
58 Years to 75 Years
Healthy volunteers
Yes
Inclusion criteria
Clinical diagnosis of PCME Cataract surgery
Exclusion criteria
diabetes vein occlusion uveitis vasculitis age-related macular degeneration hereditary macular dystrophy \-
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| the role of OCTA in diagnosis of IGS | 10 months | To evaluate the vascolarization of RPC in IGS |
Countries
Italy
Outcome results
None listed