Acute ST Segment Elevation Myocardial Infarction, Prognosis
Conditions
Brief summary
Patients with acute myocardial infarction were enrolled retrospectively. The fractional flow reserve (AccuFFR) and microcirculatory resistance index (AccuIMR) based on coronary angiography were analyzed, and the relationship between FFR and IMR and the prognosis of patients with acute myocardial infarction was analyzed
Detailed description
We retrospectively enrolled STEMI patients who underwent PCI in Peking University Third Hospital. The fractional flow reserve (AccuFFR) and microcirculatory resistance index (AccuIMR) based on coronary angiography were obtained by analyzing the coronary angiography images. The prognosis of patients was obtained by searching inpatient and outpatient systems and telephone follow-up. The relationship between AccuFFR, AccuIMR and prognosis was statistically analyzed
Interventions
DIAGNOSTIC_TESTAccuIMR and AccuFFR
AccuFFR and AccuIMR were obtained by reviewing coronary angiography at the time of primary PCI
Sponsors
Peking University Third Hospital
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Age of \>18 years; * Onset-to-treatment time of ≤12 h, meeting the diagnostic criteria for STEMI; * underwent primary PCI within 12 h of symptom onset and achieved successful PCI in the culprit vessel; * Availability of complete clinical data
Exclusion criteria
* severe tortuosity and overlap of the target vessel; * poor-quality coronary angiography images; * missing two coronary angiography images \>25° apart
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| MACE | 3 years after myocardial infarction | cardiovascular death, all-cause death, readmission for heart failure (HF), and recurrent coronary events |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| recurrent coronary events | 3 years after myocardial infarction | nonfatal myocardial infarction, unplanned PCI, and unplanned coronary artery bypass grafting |
Countries
China
Outcome results
None listed