Cervical Cancer, Radiotherapy
Conditions
Brief summary
The purpose of this study was to explore the potential application of spectral CT for radiotherapy in cervical cancer.
Interventions
RADIATIONSpectral computed tomography scan
Spectral CT scans acquisition performed during the arterial phase and venous phase for cervical cancer
Sponsors
Peking Union Medical College Hospital
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
FEMALE
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
1. All patients were confirmed cervical cancer by pathology 2. patients were treated with concurrent chemoradiotherapy 3. Spectral CT scans acquisition performed during the arterial phase and venous phase 4. All the patients underwent a 18F-FDG PET/CT before treatment
Exclusion criteria
1. CT without spectral scans 2. History of allergy to intravenous contrast 3. Pregnant or potentially pregnant female subjects
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Comparison of spectral CT derived data with response evaluation in cervical cancer | through study completion, an average of 2 year | To evaluate the tumor response of using quantitative parameters in spectral CT for cervical cancer patients according to RECIST 1.1 |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Identifying metastatic lymph nodes in cervical cancer with spectral CT | through study completion, an average of 2 year | To evaluate the diagnostic performances of using spectral CT for identifying metastatic lymph nodes in patients with cervical cancer |
| Application of energy spectrum CT in brachytherapy of cervical cancer | through study completion, an average of 2 year | The ability to reduce metal artifact and assist in target delineation |
Countries
China
Contacts
Primary ContactFuquan Zhang, Porf
Outcome results
None listed