Biological Anti-aging Efficacy of a Cosmetic Night Cream

Inclusion criteria

* Subject with phototype I, II or III according to the Fitzpatrick scale Non-inclusion Criteria: * Criteria related to the subject's health / skin : * Subject having any dermatologic condition or characteristics (like tattoo) on any of the target areas liable to interfere with the study assessments * Subject having a dermatological condition, an acute, chronic or progressive disease or history of disease liable to interfere with the study data or considered by the Investigator hazardous for the subject or incompatible with the study requirements * Subject having received on any of target areas artificial UV exposure, excessive or prolonged exposure to natural sunlight within 2 weeks before the inclusion visit or planning to be exposed to artificial UV, excessive or prolonged natural sunlight during the study and up to 3 months after completion of study participation * Subject hirsute on the target areas * Subject having contraindication to the local anaesthetic used for biopsies * Subject with known immune deficiency * Subject with a recognised addiction to alcohol or drug * Subject with a scar pathology or pathology with consequences for healing such as diabetes * Subject with known history of hepatitis B or C or known HIV positive status * Subject with hereditary or acquired haemostasis disorder * Smoker \> 10 cigarettes/day with nicotine (or equivalent in electronic cigarettes) * Criteria related to treatments and/or products: * Surgical, chemical or significant invasive treatment on any of the target areas within 6 months before the inclusion or planned during the study * Techniques with aesthetic aim on any of the target areas (laser, pulsed flash lamp etc.) or injections of reshaping products (collagen, hyaluronic acid, botulinic toxin etc.) within 6 months before the inclusion or planned during the study * Oral isotretinoin taken within 6 months before the inclusion or planned during the study * Phototherapy treatment on any of the target areas within 2 months before the inclusion or planned during the study * Systemic treatment likely to affect haemostasis (anticoagulants, platelet antiaggregants, etc.) taken within the weeks before the inclusion or planned during the study * Systemic treatment may interfere with the healing process (non-steroidal anti-inflammatory drugs, corticosteroids, immunosuppressants) taken within the weeks before the inclusion or planned during the study * Systemic treatment or topical treatment applied on any target areas likely to interfere with the local anesthetic (anti-arhythmic, beta blockers etc.) within the weeks before the inclusion or planned during the study * Topical non-steroidal anti-inflammatory, dermocorticoids, immunomodulators applied on any of the target areas within the 2 weeks before the inclusion or planned during the study * Topical skincare product (e.g. exfoliation, scrub, body mask) applied on any of the target areas within 7 days before the inclusion or planned during the study