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Postoperative Pain for Patients After TA-BSM

Effect of Thoracic Paravertebral Nerve Block on Postoperative Pain After Transapical Beating-heart Myectomy(TA-BSM) in Patients With Hypertrophic Obstructive Cardiomyopathy: a Retrospective Cohort Study

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06433089
Enrollment
197
Registered
2024-05-29
Start date
2023-04-01
Completion date
2024-04-30
Last updated
2024-05-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Nerve Block, Transapical Beating-heart Septal Myectomy

Brief summary

To retrospectively analyze the intraoperative and postoperative status of patients with hypertrophic cardiomyopathy undergoing TA-BSM, and to estimate whether paravertebral nerve block can improve postoperative pain for these patients.

Detailed description

Since conventional septal myectomy can be only assessed when the heart resumes beating, and the complications induced by cardiopulmonary bypass are inevitable, a novel transapical beating-heart septal myectomy (TA-BSM) has been invented, which provides real-time evaluation to guide resection while reducing surgical trauma. Postoperative pain after TA-BSM is unknown. Whether paravertebral nerve block can improve postoperative pain caused by TA-BSM is the objective of our study.

Interventions

PROCEDUREThoracic paravertebral block

Thoracic paravertebral block was performed before surgery

Sponsors

Wenlong Yao (101480)
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to 75 Years
Healthy volunteers
No

Inclusion criteria

* Age 18\ 75 years * American society of anesthesiologists classification II-III * Elective TA-BSM was performed

Exclusion criteria

* Underwent multiple surgical procedures or required cardiopulmonary bypass assistance * Combined other function decompensation disease * Patients with incomplete medical records

Design outcomes

Primary

MeasureTime frameDescription
Morphine consumptionDuring the first 48 hours after surgeryCumulative morphine consumption

Secondary

MeasureTime frameDescription
Postoperative pain score 2Day 7 after surgery and month 3 after surgeryBrief Pain Inventory(The degree of pain \[0 no pain to 10 very painful\] and the impact of pain on daily life function \[0 no impact to 10 very impact\])
Physical recovery after surgeryDay 7 after surgeryQuality of recovery(Rating from 0 \[very poor\] to 150 \[excellent\])
Complications24 hours and 48 hours after surgeryThe incidence of nausea and vomiting
Perioperative information 1Immediately after the surgeryThe usage of analgesic drug
Postoperative pain score 124 hours after surgery and and 48 hours after surgeryVisual Analogue Scale score(0-10 stands for the degree of pain, 0=no pain, 10=the worst pain ever)
Perioperative information 3P1= before induction, P2= 5 minutes after tracheal intubation, P3= before skin incision, P4= 5 minutes after skin incision, P5=5 minutes after placed the rib spreaderHeart reat
Perioperative information 4Immediately after the surgeryDuration of anesthesia
Postoperative information 1Postoperative in 24 hoursExtubation time
Postoperative information 2Postoperative in 48 hoursThe usage of analgesic drug
Perioperative information 2P1= before induction, P2= 5 minutes after tracheal intubation, P3= before skin incision, P4= 5 minutes after skin incision, P5=5 minutes after placed the rib spreaderMean arterial blood pressure

Countries

China

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026