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Knee Osteoarthritis and Rehabilitation

Knee Osteoarthritis and Lazer Therapy

Status
Recruiting
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT06432842
Enrollment
30
Registered
2024-05-29
Start date
2023-07-01
Completion date
2024-06-30
Last updated
2024-05-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Knee Osteoarthritis

Keywords

Osteoarthritis, Intra-articular injection, PRP (Platelet-rich plasma), Physiotherapy, Laser Treatment

Brief summary

Osteoarthritis (OA) is a chronic degenerative disease of articular cartilage that causes hypertrophic changes in bone. OA is a non-inflammatory progressive musculoskeletal disease and is one of the most common degenerative diseases in the general population. OA is characterized by progressive cartilage destruction in load-bearing joints, subchondral sclerosis, osteophyte formation, and some biochemical and morphological changes in the synovial membrane and joint capsule. Common symptoms of knee osteoarthritis are; Knee pain that increases with activity, limitation of normal joint movement of the knee, edema, and knee pain that begins with prolonged sitting. The aim of this study is to evaluate the effects of laser treatment applied in addition to conventional physiotherapy on pain, function, muscle strength and balance in patients with knee osteoarthritis who received PRP.

Detailed description

OA is a non-inflammatory progressive musculoskeletal disease; damage begins in the cartilage and causes changes in the joint structure over time. Although intra-articular injection approaches have been frequently used in the treatment of OA recently, intra-articular injections known as Platelet Rich Plasma (PRP) have also started to be used frequently. Today, the areas of use of laser therapy have increased. When the laser beam is applied, it is absorbed by the tissue or scattered back. Laser has photochemical, thermal and ionizing effects on tissues. Laser has an analgesic effect by increasing endorphin synthesis and reducing C nerve fiber activation. Laser indirectly increases microcirculation by increasing temperature in the tissue. Although there are various studies on treatment options for OA in the literature, no studies have been found to investigate the effectiveness of laser treatment applied in addition to conventional treatment after PRP. In our study, we aimed to evaluate the effects of laser treatment applied in addition to conventional physiotherapy on pain, function, muscle strength and balance in patients with knee osteoarthritis who received PRP.

Interventions

OTHERLaser Treatment

In the study group, low-dose laser treatment was applied in addition to conventional treatment. Chattanoga Group Therapeutic Laser device was used for laser treatment. Laser treatment was applied to 8 sensitive points around the knee for 1 minute, for a total of 8 minutes. Laser treatment was applied continuously, with a wavelength of 830nm and a power of 6J.

Sponsors

Karabuk University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Subject)

Eligibility

Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
No

Inclusion criteria

* Volunteering to participate in the study * Being diagnosed with knee OA by a specialist physician * Having had PRP injection applied by a specialist physician * Having unilateral knee OA * Being stage I-stage III in the Kellgren-Lawrence OA classification * Being between the ages of 18-65

Exclusion criteria

* Being stage IV in the Kellgren-Lawrence OA classification * BMI being more than 40 kg/m2 * Patients who do not cooperate well * Patients with neurological or neuromuscular disease

Design outcomes

Primary

MeasureTime frameDescription
Pain severityBaseline and 2 weeks post-interventionKnee pain severity will measured using the Visual Analog Scale. Scale (VAS). The VAS is a 10 cm scale, where 0 represented no pain and 10 represented unbearable pain. Pain intensity was recorded by measuring the point marked between 0- 10.
Function2 weeks post-interventionWOMAC will be used to evaluate the degree of physical function. This scale has a total of 24 questions and 5 answers between 0-4 for each question. A high score indicates that the symptoms are severe.
MUSCLE STRENGTHBaseline and 2 weeks post-interventionHip, knee flexor and extensor muscle strengths will be measured using a manual dynamometer.
BALANCEBaseline and 2 weeks post-interventionDynamic balance of individuals through the Modified Star Balance Test will be evaluated.

Countries

Turkey (Türkiye)

Contacts

Primary ContactSevde Nur AKTAŞ, MsC
sevdenur9880@icloud.com05438760764
Backup ContactMetehan YANA, PhD
metehanyana@karabuk.edu.tr05072665522

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026