Campylobacter Infections
Conditions
Keywords
primary immunodeficiency, Campylobacter, Relapsing bacteraemia
Brief summary
Some rare cases of recurrent Campylobacter bacteraemia (RCB) exist with relapses months to years after an effective treatment and a negativation of all bacterial samples. As of today, only around 20 cases have been described in the international literature for the last 30 years. The cases are likely highly underreported. No study describes those recurrent Campylobacter bacteraemias at the scale of a country. The aim of this multicentre, nationwide, retrospective study is to describe their precise epidemiology in France for the last 25 years, the immune profile of the patients, the specificities of the bacteria involved, the treatments received and the evolution of these infections. The perspective is to propose a standardization of the medical care of those patients mainly by describing the effective treatments and the explorations of the immune system which should be considered.
Interventions
OTHERCharacteristics of patients and Campylobacter bacteraemia episodes
Variables: characteristics of the patients (demographic characteristics; characteristics of immunodeficiency: diagnosis, immunoglobulin dosage, white cells count etc.; chronic inflammatory bowel disease \[IBD\]), the bacteria (species, antimicrobial susceptibility) and the infection (clinical presentation, evolution, treatment received)
Sponsors
Hospices Civils de Lyon
Study design
Observational model
CASE_ONLY
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
No minimum to 100 Years
Healthy volunteers
No
Inclusion criteria
* 2 episodes or more of Campylobacter bacteraemia separated by at least 60 days * AND immunodeficiency condition * followed by a French hospital
Exclusion criteria
-Opposition of the patient
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Description of the characteristics of the patients presenting with recurrent Campylobacter bacteraemia | Baseline | -demographic characteristics |
Countries
France
Contacts
Primary ContactAnne CONRAD, Dr
Backup ContactNicolas BENECH, Dr
Outcome results
None listed