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Identification of Post-Traumatic Stress Disorder in Adult Patients With Substance Use Disorders

Identification of Post-Traumatic Stress Disorder in Adult Patients With Substance Use Disorders Followed up in the Medical and Psychological Centre: Multicentre Descriptive Study

Status
Withdrawn
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT06432400
Acronym
IRTIPAP
Enrollment
0
Registered
2024-05-29
Start date
2024-12-31
Completion date
2025-12-31
Last updated
2025-03-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Trauma

Keywords

Post Traumatic Stress Disorder, Complex post traumatic stress disorder, Medical and Psychological Centre

Brief summary

The aim of this study is to show that early identification of PTSD and CPTSD would increase recognition of these disorders and facilitate diagnosis, referral and recovery.

Detailed description

Between 61% and 81% of men and 51% to 74% of women are exposed to a traumatic event in their lifetime. These events may be brief and discrete, prolonged and/or recurrent, and may be direct or indirect. Direct or indirect exposure to traumatic events can lead to serious negative psychological consequences, including post-traumatic stress disorder (PTSD) and complex post-traumatic stress disorder (CPTSD). People exposed to complex traumatic events are at risk not only of suffering from PTSD or Complex PTSD, but also from other mental health co-morbidities, such as substance use disorders (drugs, alcohol, benzodiazepine misuse) , often associated with the repetition of situations of interpersonal violence from which it is difficult, if not impossible, to escape. Caring for people suffering from psychological trauma is a major public health issue. However, there are no good clinical practice guidelines for diagnosis, assessment and treatment, which would enable good practice to be standardised and disseminated. The prevention, detection, early support and appropriate guidance of people suffering from post-traumatic sequelae promote their recovery and improve their quality of life. The World Health Organization (WHO) refers to this as psychological distress, and points out that if it is not properly identified or accompanied, it can tip a person into illness or increase social difficulties. When it is temporary and follows a stressful event, it is considered a normal adaptive reaction. On the other hand, when it becomes intense and persistent, it may be an indicator of a psychological disorder. The public health challenge associated with PTSD is to better recognise, diagnose and treat it, as it can have serious consequences for the quality of life, social functioning and suicide risk of those affected. The aim of this study is to show that early identification of PTSD and CPTSD would increase recognition of these disorders and facilitate diagnosis, referral and recovery. It would also make it possible to provide individualised support for patients and improve their quality of life.

Interventions

Patients questionnaires, on paper and data collection on patients medical file

Sponsors

Hôpital NOVO
Lead SponsorOTHER

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
OTHER
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

: * Patient aged 18 or over * Patient followed up at the adult Medical and Psychological Centre in the centres taking part in the study * Patient suffering from disorders related to the use of alcohol, cannabis, opiates, inhalants, sedatives, hypnotics, anxiolytics, stimulants, hallucinogens (all of these disorders will have been diagnosed by a doctor before or during follow-up according to DSM 5 criteria). * Patient aware of their substance use disorders * Patient informed and did not object to participating in the study

Exclusion criteria

: * Patient previously diagnosed with PTSD or CPTSD * Patient agitated and/or aggressive * Patient under guardianship/curators * Patient who do not speak or understand French

Design outcomes

Primary

MeasureTime frameDescription
Assessment of the proportion of Post-Traumatic Stress Disorder (PTSD) in patients with substance use disordersAt the end of the study, an average of 12 monthPercentage of patients with PTSD among those with substance use disorders Patients with PTSD will be identified using the International Trauma Questionnaire (ITQ) : A diagnosis of PTSD requires the presence of at least one symptom in each of the following dimensions * P1 or P2 ≥ 2 * P3 or P4 ≥ 2 * 5 or P6 ≥ 2 AND * P7 or P8 or P9 ≥ 2 Score ITQ for PTSD : ≥ 8

Secondary

MeasureTime frameDescription
Distinguishing between the prevalence of Post-Traumatic Stress Disorder (PTSD) and Complex Post-Traumatic Stress Disorder (CPTSD)At the end of the study, an average of 12 monthPercentage of patients with CPTSD among those with substance use disorders Patients with CPTSD will be identified using the International Trauma Questionnaire (ITQ) : A diagnosis of CPTSD requires a PTSD : ≥ 8 and, at least, one symptom in each of the dimensions of disturbance of self-organisation * C1 or C2 ≥ 2 * C3 or C4 ≥ 2 * C5 or C6 ≥ 2 AND * C7 or C8 or C9 ≥ 2 Score ITQ for CPTSD : ≥ 16
Identification of risk factors by comparing demographic data of PTSD versus CPTSD patientsAt the end of the study, an average of 12 monthRisk factors will be identified from the demographic data collected via the patient characteristics questionnaire between PTSD and CPTSD patients
Identification of the pathologies most associated with PTSD and CPTSDAt the end of the study, an average of 12 monthThe pathologies most frequently associated with PTSD and CPTSD will be identified by collecting the pathologies present in the medical records of all patients.
Comparison of the time between management and identification of patients with PTSD versus CPTSDAt the end of the study, an average of 12 monthComparison for number of days between the start of treatment for substance use disorders and the identification of PTSD or CPTSD

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026