Tattoo Particles: Picosecond Laser Versus Nanosecond Laser

In Vivo Analysis of Tattoo Particles After Picosecond Laser Compared to Nanosecond Laser

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT06431464

Enrollment

Registered

2024-05-28

Start date

2024-02-01

Completion date

2024-07-31

Last updated

2024-05-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Tattoo; Pigmentation

Brief summary

\- For treating unwanted tattoos, the gold standard treatment is a nanosecond or picosecond laser. However, comparative microscopic analysis is limited. Therefore, the aim of the present study is to analysis morphological changes of tattoo particles and surrounding tissue in human skin.

Interventions

OTHERpicosecond laser treatment + measurement with a multiphoton tomography system

Patients with unwanted tattoos who plan a laser treatment will be recruited for measurements using a multiphoton-tomography system. These are scheduled 6 weeks and 12 weeks post-treatment.

OTHERnanosecond laser treatment + measurement with a multiphoton tomography system

Patients with unwanted tattoos who plan a laser treatment will be recruited for measurements using a multiphoton-tomography system. These are scheduled 6 weeks and 12 weeks post-treatment.

Study design

Observational model

CASE_CONTROL

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Inclusion criteria

\- healthy patients who plan a laser treatment of their unwanted tattoo/ tattoos at our department

Exclusion criteria

* laser pretreatment of their tattoos to be treated * pregnancy, breast feeding * open wound on the area to be treated

Design outcomes

Primary

Measure	Time frame	Description
Size of intercellular spaces	6 weeks and 12 weeks post-treatment	Size of intercellular spaces after picosecond or nanosecond laser treatment.
Size of keratinocytes	6 weeks and 12 weeks post-treatment	Size of keratinocytes after picosecond or nanosecond laser treatment.
Size of tattoo particles	6 weeks and 12 weeks post-treatment	Size of tattoo particles after picosecond or nanosecond laser treatment.
Distribution of tattoo particles	6 weeks and 12 weeks post-treatment	Distribution though the epidermal and dermal layers after picosecond or nanosecond laser treatment.

Countries

Germany

Contacts

Primary ContactLynhda Nguyen, Dr. med.

l.ngyuen@uke.de+49 (0) 7410-0

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026