Prospective Observational Cohort Study of Transplant and Cell Therapy Candidates and Recipients to Assess Social Determinants of Health

Conditions

Transplant and Cell Therapy

Keywords

Social Determinants of Health

Brief summary

To learn more about social and financial factors that may influence outcomes of TCT treatment at MD Anderson.

Detailed description

Primary Objective: To determine the relationship between participant social determinants of health (SDOH) and outcomes following transplantation and cellular therapy at MDACC.

Caitlin Sarubbi, Jennifer Miatech, Mark Forsberg, Asha Elsa Demla, Zara Rahman et al. (40 authors)

Blood2025-11-03

10.1182/blood-2025-4392

Prospective observational cohort study to collect granular social determinants of health data for hematopoietic cell transplant patients

Warren Fingrut, KaNoisha Codrington, Denái R. Milton, Ligny Hunter, Ricky Garcia et al. (9 authors)

Blood2025-11-03

10.1182/blood-2025-6163

Prospective Observational Cohort Study to Collect Granular Social Determinants of Health Data for Transplant and Cellular Therapy Candidates and Recipients

Warren Fingrut, KaNoisha Codrington, Ligny Hunter, Ricky Garcia, Charles Martinez et al. (9 authors)

Blood2024-11-051 citations

10.1182/blood-2024-202666

Interventions

BEHAVIORALSocial Determinants of Health Questionnaire

Participants will also complete a questionnaire about financial barriers to care within the past year, including income bracket and difficulty affording cost-of-living or medical expenses.

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

No

Inclusion criteria

1. ≥ 18 years of age. 2. Received financial clearance for TCT. Qualitative study - patients 1. Patient ≥ 18 years of age who is currently cared for at MD Anderson as a TCT candidate/ recipient, 2. The patient reports social and/or financial challenges impacting care delivery. 3. The patient is willing to participate in a semi-structured interview. Qualitative study - caregivers 1. Caregiver(s) of a patient ≥ 18 years of age who is currently cared for at MD Anderson as a TCT candidate/ recipient. 2. The patient reports social and/or financial challenges impacting care delivery. 3. The patient has referred the caregiver(s) to participate and provided us with permission to contact their caregiver(s). 4. The caregiver(s) is (are) willing to participate in a semi-structured interview.

Exclusion criteria

Patients - Quantitative study 1) Did not receive financial clearance for TCT Patients - Qualitative study 1\) Not impacted by social or financial challenges. Caregivers (qualitative study) 1. Did not care for a patient impacted by social or financial challenges 2. Were not referred to participate in the study by patient they cared for.

Design outcomes

Primary

Measure	Time frame
Social Determinants of Health Questionnaire	At 6, 12, 18, and 24 months post Transplant and Cell Therapy

Countries

United States

Contacts

CONTACTWarren Fingrut, MD

wbfingrut@mdanderson.org(832) 387-8363

PRINCIPAL_INVESTIGATORWarren Fingrut, MD

M.D. Anderson Cancer Center

Outcome results

None listed