Cesarean Section Complications, Morbidity;Perinatal, Postpartum Hemorrhage
Conditions
Keywords
cesarean section, postpartum hemorrhage, maternal morbidity, obstetrics comorbidity index
Brief summary
The objective of this study is to examine the predictive capability of the Obstetric comorbidity index in the identification of severe maternal morbidity associated with postpartum hemorrhage in patients undergoing cesarean delivery.
Detailed description
The prospectively predictive maternal morbidity is imperative to enhance maternal outcomes. There has been development of the obstetric comorbidity index (OBCMI) by Bateman et al. in 2013 and performed with superior performance characteristics relative to general comorbidity measures in an obstetric population. The score has been a growing recognition of the necessity for specialized risk assessment tools tailored specifically to obstetric populations that differ from other populations. For instance, both the Charlson/Romano comorbidity index or the Elixhauser comorbidity score and their adaptations are deficient in accounting for obstetric conditions, thereby limiting their ability to predict obstetric morbidity or mortality. The Obstetric Comorbidity Index has undergone thorough examination and validation across multiple nations. These findings collectively demonstrate the index's capacity for moderate to high predictive accuracy in anticipating maternal morbidities, accompanied by a commendable discriminative performance. However, within the context of Thailand, investigations concerning the Obstetric Comorbidity Index and its association with perioperative complications or morbidities in postpartum hemorrhage patients undergoing cesarean delivery remain unexplored. Therefore, this study aims to elucidate the correlation between the Obstetric Comorbidity Index and severe maternal morbidity, while also scrutinizing the prevalence of comorbidities during the perioperative period among patients undergoing cesarean delivery at the largest University hospital, in THAILAND. Predicting the rate of maternal morbidity would be advantageous for facilitating preparation and augmenting awareness of complications during the perioperative period.
Interventions
OTHERObstetric comorbidity index
Obstetric comorbidity index score
Sponsors
Mahidol University
Study design
Observational model
OTHER
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
FEMALE
Healthy volunteers
No
Inclusion criteria
The patients underwent cesarean delivery with the diagnosis of postpartum hemorrhage (ICD-10 coding O72.1)
Exclusion criteria
* Cesarean delivery at less than 24 weeks of gestation * A patient chart that does not contain primary outcome data eg. absence of anesthetic record * Blood loss less than 1,000 ml in the first 24 hours postpartum
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| The prediction of severe maternal morbidity using obstetric comorbidity index | in 72 hours after cesarean delivery | The prediction of severe maternal morbidity using obstetric comorbidity index presented in C-statistic (AUC of ROC) |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Rate of maternal mortality | in 72 hours after cesarean delivery | Maternal death rate |
| Rate of blood transfusion | in 72 hours after cesarean delivery | Perioperative red blood cells transfusion in units |
| Quantity of postpartum hemorrhage | in 24 hours after cesarean delivery | Quantity of postpartum hemorrhage in ml. |
| Neonatal Apgar score | at 1-minute and 5-minute after delivery | Neonatal Apgar score from 0 - 10 |
| Rate of ICU admission | in 24 hours after cesarean delivery | Rate of intensive care unit admission |
| Rate of Postoperative complications | in 72 hours after cesarean delivery | Post operative complications eg. congestive heart failure, TRALI, acute kidney injury |
| Cause of postpartum hemorrhage | in 24 hours after cesarean delivery | Main cause of postpartum hemorrhage |
Countries
Thailand
Outcome results
None listed