Esophageal Cancer
Conditions
Brief summary
The purpose of the study is to examine the feasibility and acceptability of exercise prehabilitation for patients preparing for esophageal cancer resection (removal).
Interventions
BEHAVIORALExercise
Physical activity and resistance training
Sponsors
H. Lee Moffitt Cancer Center and Research Institute
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
SUPPORTIVE_CARE
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Biopsy-proven locoregional esophageal cancer (LEC) * Eastern Cooperative Oncology Group (ECOG) performance status 0-2 * Treatment plan including neoadjuvant chemoradiation therapy and surgical resection * Ability to read and speak English
Exclusion criteria
* Regular engagement in resistance training (2x/week targeting all major muscle groups) * Screen failure for exercise safety based on PAR-Q * Underlying unstable cardiac or pulmonary disease or symptomatic cardiac disease * Recent fracture or acute musculoskeletal injury that precludes ability to participate in resistance training safely * Numeric pain rating scale of 7 or more out of 10 * Myopathic or rheumatologic disease that impacts physical function
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Retention | Up to 11 weeks | The number of participants who complete T0 and T1 measures. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Exploratory outcomes and changes | Up to 17 weeks | The number of participants who demonstrate improvements in exploratory outcome measures. |
| Clinical and treatment outcomes | Up to 17 weeks | Chi-square testing will be used to determine if there's a difference in perioperative outcomes between groups. |
Countries
United States
Contacts
Primary ContactNathan Parker, PhD
Outcome results
None listed