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Incidence of Early Infection After Bipolar Hemiarthroplasty and Its Associated Factors in Fracture Neck of Femur

Incidence of Early Infection After Bipolar Hemiarthroplasty and Its Associated Factors in Fracture Neck of Femur

Status
Not yet recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06427772
Enrollment
74
Registered
2024-05-24
Start date
2024-06-01
Completion date
2025-06-30
Last updated
2024-05-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Prosthetic-joint Infection

Brief summary

Periprosthetic joint infections (PJI) following hemiarthroplasty for hip fractures are a catastrophic complication that results in severe worsening of patients' daily function and quality of life. The incidence of prosthetic joint infection (PJI) in hemiarthroplasty after femoral neck fracture varies from 2% to 17%. Identifying risk factors associated with early infection following HA for hip fractures may provide an opportunity to treat and prevent this potential complication with preoperative planning in many patients. So investigators will study the rate of early infection and its associated factor after bipolar hemiarthroplasty.

Detailed description

Femoral neck fractures (FNF) have a significant incidence and a rising trend worldwide. FNF is associated with a high mortality and disability rate, decreasing the independence and quality of life for affected patients. Acute displaced intracapsular femoral neck fractures account for about half of all hip fractures, with the majority of these fractures in older patients being treated surgically with hip hemiarthroplasty(HA), total hip arthroplasty, or internal fixation. Hemiarthroplasty is also used to treat femoral neck nonunion, failed screw fixation, and pathological femoral neck fracture. The treatment aims are to reduce pain, allow early mobilization, and restore the patient's pre-injury level of function while limiting perioperative surgical and medical complications. Patients with FNF frequently undergo hemiarthroplasty to restore joint biomechanics. Two types of implants are used in hemiarthroplasty: monopolar and bipolar . The bipolar implants have a polyethylene bearing between the stem and head of the endoprosthesis, which allows the components to rotate. There are debatable findings and a lack of consensus on the optimal component for hemiarthroplasty. Periprosthetic joint infections (PJI) following hemiarthroplasty for hip fractures are a catastrophic complication that results in severe worsening of patients' daily function and quality of life. The incidence of prosthetic joint infection (PJI) in hemiarthroplasty after femoral neck fracture varies from 2% to 17%. Identifying risk factors associated with early infection following HA for hip fractures may provide an opportunity to treat and prevent this potential complication with preoperative planning in many patients. So investigators will study the rate of early infection and its associated factor after bipolar hemiarthroplasty.

Interventions

bipolar hemiarthroplasty for neck femur fracture

Sponsors

Assiut University
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL

Inclusion criteria

* Patients with femoral neck fractures and treated by bipolar hemiarthroplasty. * Patients or their legal representative able to give informed consent.

Exclusion criteria

* Patients that received HA secondary to a failed internal fixation of a femoral neck fracture. * Patients with a pathological fracture due to malignancy.

Design outcomes

Primary

MeasureTime frameDescription
incidence of early infection after bipolar hemiarthroplasty4 weeks postoperativeinvestigators will take all cases with bipolar hemiarthroplasty after femoral neck fracture then follow up them for 4 weeks. An infection was categorized as early, if it occurred within 4 weeks after surgery After that investigators will classify them to infected (disease group) and non infected (control group) and studying risk factor predisposing to early infection after HA. For diagnosis of infection : the presence of persistent discharge after 7 days
risk factor predisposing to early infection after HA.1-preoperative parameters :Patient agepreoperative evaluation 1 weekAge in years
risk factor predisposing to early infection after HA.1-preoperative parameters :sexpreoperative evaluation 1 weekmale or female
risk factor predisposing to early infection after HA.1-preoperative parameters :Chronic diseases as Diabetes, rheumatoid arthritis and other inflammatory or autoimmune arthritis.preoperative evaluation 1 weekpresent or not
risk factor predisposing to early infection after HA.1-preoperative parameters : • Active skin disease (at site of surgical incision)preoperative evaluation 1 weekpresent or not
risk factor predisposing to early infection after HA.1-preoperative parameters : • Smoking and alcohol consumptionpreoperative evaluation 1 weekyes or no
risk factor predisposing to early infection after HA.1-preoperative parameters : • Distant septic focus after arthroplasty as (pneumonia ,UTI ,abdominal ,oral and cutaneous infection).preoperative evaluation 1 weekpresent or no
risk factor predisposing to early infection after HA.2-intraoperative parameters : • Surgery time .at time of operationin hours
risk factor predisposing to early infection after HA.2-intraoperative parameters :• Appropriate antibiotics prophalyxis and Need to blood transfusion.at time of operationyes or no
risk factor predisposing to early infection after HA.3-postoperative parameters :• Persistent drainage after 7 days.1 week postoperativetime in days

Contacts

Primary ContactAhmed Sallam AboElazaiem, bachelor's
ahmedsallam2020159@gmail.com01005732964

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026