Volume Effect in Peng Block for Total Hip Replacement

Peng Block in Total Hip Replacement: Effects of Anesthetic Volume on Clinical Outcome and Postoperative Complications

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT06427551

Acronym

volupeng

Enrollment

120

Registered

2024-05-24

Start date

2022-01-01

Completion date

2024-01-30

Last updated

2024-05-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anesthesia, Post Operative Pain

Keywords

postoperative, orthopedic surgery

Brief summary

This study is to investigate whether a different volume of ropivacaine, with the same prescribed dosage based on body weight, can affect block efficacy, duration and side effects in the first 24 hours postoperatively.

Detailed description

patients were divided into 3 groups on the basis of the volume of anesthetic given to perform the block. in every patient was assessed the nrs, the side effects, if any, and the need for analgesic drugs in the first 24 hour after surgery

Interventions

DRUGRopivacaine

The local anesthetic was dosed on the patient's weight (50-59kg: 120mg, 60-61kg: 140mg, 70-79kg: 160mg, ≥80kg: 180mg)

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* ASA I, ASA II, ASA III * Age≥18 * Total hip replacement surgery in spinal anesthesia * Informed consent

Exclusion criteria

* ASA IV * INR\>1.3 * platelet values\<100\*10\^3/ml a * patients on anticoagulant or antiplatelet therapy * general anesthesia for total hip replacement surgery * patients on chronic opioid therapy * altered sensitivity or motility * Patients in chronic opioid therapy * Refuse to sign informed consent form * Unable to sign informed consent form * Know allergies to medication used for analgesia

Design outcomes

Primary

Measure	Time frame	Description
NRS evaluation	24h post-op	Evaluate pain for every volume group in the first 24 hours post surgery using the Numeric Pain Scale (NRS) assigning a numeric value between zero (no pain) and ten (the worst pain ever felt). Absence of relevant pain is considered a NRS less than three. Success of the block was defined as NRS≤3.

Secondary

Measure	Time frame	Description
NRS variation in time	24 h	consider variation of pain, assessed with numeric Pain scale, for each group, every six hours

Other

Measure	Time frame	Description
presence of side effects	24 hours	Monitoring the onset of side effects (nausea/vomiting/hypotension/dizziness/sensitive impareiment) in every group of patients in the first 24 hours every six hours
analgesic requirements	24 hours	requirement of analgesic to control the pain, assessed every six hours

Countries

Italy

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026