Allergy in Children
Conditions
Brief summary
The present study will investigate the long term effect of allergen immunotherapy in a real-life study in children with allergy undergoing subcutaneous or sublingual immunotherapy with grass pollen, birch, house dust mites or venom.
Detailed description
The study will include children aged 5- 18 years who are treated with immunotherapy at Hans Christian Andersen Children' Hospital, Odense University Hospital. Informed consent to be registered in a database and to receive a questionnaire 5 and 10 years after end of treatment are obtained before start of immunotherapy. Base line data include information from the patient record: symptoms, medication, blood test and skin prick test results. During treatment effect, medication use, lung function and adverse events are monitored systematically once a year. The questionnaires 5 and 10 years after end of treatment will focus on allergy symptoms, use of medication and asthma symptoms.
Interventions
Patients will be treated as usual. The study is an observation of the long term effect of the treatment
Sponsors
Odense University Hospital
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
4 Years to 18 Years
Healthy volunteers
No
Inclusion criteria
treated with allergen immunotherapy at HCA Children'sHospital, Odense University Hospital -
Exclusion criteria
received less than 12 months of treatment with allergen immunotherapy \-
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Effect of immunotherapy 5 years after end of treatment | 5 years | Medication use for allergy and asthma and the patient's experience of effect of the AIT on a scale from 0-4 (0= no effect, 1= modest effect, 2= some effect, 3= good effect, 4= very good effect) |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Effect of immunotherapy 10 years after end of treatment | 10 years | Medication use for allergy and asthma and the patient's experience of effect of the AIT on a scale from 0-4 (0= no effect, 1= modest effect, 2= some effect, 3= good effect, 4= very good effect) |
Countries
Denmark
Contacts
Primary ContactJosefine Gradman, PhD
Outcome results
None listed