Autism Spectrum Disorder High-Functioning
Conditions
Brief summary
The main aim of the study is to investigate whether APP-based emotional recognition training improve social function in autistic children.
Detailed description
50 ASD children age ranged from 4-10 years old will be randomly allocated to either app-based emotional recognition training or memory training groups for 2 months. Before and after training, some assessements were measured including Autism Diagnostic Observation Schedule-2, Childhood Autism Rating Scale, Wechsler Intelligence Scale and Psychoeducational Profile-3. Some other questionnaires are also collected including Social Responsibility Scale-2,Repetitive behavior scale-Revised,Caregiver Strains Questionnaire，Social Communication Questionnaire，Social Anxiety Scale for Children，Adaptive behavior assessment Schedule. Four eye-tracking tasks as follows: (1) Dynamic geometrical paired with dynamic child dancing; (2) Static neutral and emotional faces; (3) A dynamic gaze-following task; (4) social interaction behaviors paired with the toys alone; (5) spinning actions conducted via children paired with objects.
Interventions
BEHAVIORALAPP-based emotion recognition intervention
ASD children were asked to play emotion recognition-related games for eight weeks using iPAD. Two 15-minsute sessions each day was required.
BEHAVIORALAPP-based memory intervention
ASD children were asked to play memory-related games for eight weeks using iPAD. Two 15-minsute sessions each day was required.
Sponsors
University of Electronic Science and Technology of China
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Investigator, Outcomes Assessor)
Intervention model description
Experimental group (emotion recognition); control group (memory training)
Eligibility
Sex/Gender
ALL
Age
4 Years to 10 Years
Healthy volunteers
No
Inclusion criteria
Clinical diagnosis of Autism Spectrum Disorder and follow these criteria: (1) Age range: 4-10 years old, gender not limited;(2) Ethnicity: Han nationality;(3) Autism Diagnostic Observation Schedule-Second Edition (ADOS-2) Comparison Score greater than or equal to 5 points (Le et al., 2022);(4) Considering that only high-functioning autism individuals can successfully complete the eye-tracking tasks, children with a Wechsler score greater than or equal to 60 points are selected;
Exclusion criteria
(1) No neurological complications, such as epilepsy, cerebral palsy, fragile X syndrome, etc.;(2) No prior medical interventions, such as taking antipsychotic drugs, receiving transcranial magnetic stimulation, acupuncture, etc.;(3) No abnormal imaging diagnosis or any brain injury.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| ADOS-2 assessment | 1-2 hour | ADOS-2 assessment |
| SRS-2 | half an hour | SRS-2 |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Visual performance across five tasks based on eye-tracking | half an hour | Tasked based eye-tracking performance including fixation time, fixation counts |
Other
| Measure | Time frame | Description |
|---|---|---|
| Other questionnaires and assessment | 1-2 hour | CARS |
Countries
China
Outcome results
None listed