Head and Neck Carcinoma
Conditions
Brief summary
This study evaluates the cell and biomarkers associated with the aggressive behavior of cancer.
Detailed description
PRIMARY OBJECTIVE: I. High-resolution single-cell profiling of Cancer-associated fibroblasts (CAFs) in Human papillomavirus (HPV)+ Oropharyngeal Squamous Cell Carcinoma (OPSCC) and metastatic lymph nodes. OUTLINE: This is an observational study. Patients undergo photography, blood sample collection, tissue collection and have their medical records reviewed on study.
Interventions
OTHERNon-Interventional Study
Non-interventional study
Sponsors
University of Southern California
National Cancer Institute (NCI)
American Academy of Otolaryngology-Head and Neck Surgery Foundation
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Diagnosis/disease status: New diagnosis of head and neck cancer * Allowable type and amount of prior therapy: No prior treatment * Age ≥ 18 years. * Ability to understand and the willingness to sign a written informed consent.
Exclusion criteria
* Patients who have had treatment of head and neck cancer
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Overall survival | Up to 5 years |
| Disease free survival | Up to 5 years |
Countries
United States
Contacts
CONTACTSandy Tran, MS
PRINCIPAL_INVESTIGATORAlbert Y Han, MD
University of Southern California
Outcome results
None listed