Healthy Elderly, Mild Cognitive Impairment (MCI)
Conditions
Keywords
Functional near infrared spectroscopy, Parameters of digit force independence, Pressing Evaluation and Training System
Brief summary
Previous studies indicated that auditory stimulation as an external cue might have positive impacts on sensorimotor synchronization. Additionally, according to previous reports apart from traditional interventions, digitized game-based device, such as FTOMBVG, are beneficial for the brain activation in elderly. Moreover, enhanced finger force control and coordination lead to better hand dexterity and is believed to eventually improve life independence in the healthy elderly and the elderly with cognitive decline. Therefore, this study aims to develop an advanced systems based on the previous one, that can provide hand function rehabilitation, cognitive training, and emotional comfort for the elderly or people suffer from cognitive deficiency. They can enhance their finger force control or visual to motor synchronization by music embedded during the gaming process.
Interventions
DEVICEGame Software
The software is interfaced with a modified version of Frets on Fire (FOF)-an open source computer game similar to Guitar Hero.
Sponsors
National Cheng-Kung University Hospital
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
PREVENTION
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
65 Years to 90 Years
Healthy volunteers
Yes
Inclusion criteria
* Ability to communicate in Mandarin Chinese or Taiwanese * MCI, according to clinical neurological assessment, Montreal Cognitive Assessment (MoCA):≦25&≧19 * Ability to perform ADL independently, no hand function disability * Voluntarily participation and ability to sign the informed consent form
Exclusion criteria
* Alzheimers disease diagnosed by physicians or meeting the diagnostic criteria for dementia * Physician's diagnosis of stroke * Any mental illness or behavior problems and inability to cooperate with the trainer * Visual impairment or hand diseases resulting in an inability to perform finger press * received other cognitive or physical training in the past year * any sight, hearing, or communication impairment
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Oxygenated hemoglobin (HbO) | 30 minutes | The Oxygenated hemoglobin (HbO) was measured while the participants play the game under both conditions |
| Montreal Cognitive Assessment (MoCA) test | 10 minutes | The Montreal Cognitive Assessment (MoCA) was designed as a rapid screening instrument for mild cognitive dysfunction. It assesses different cognitive domains: Short term memory, Visuospatial abilities, Executive functions, Attention, concentration and working memory, Language, Orientation to time and place. The sensitivity of MoCA for detecting MCI is 90%. |
| EN value | 5 minutes | The force independence is collected from the data during force control game in each evaluation session. The parameter of force independence is an index of five digits overall enslaving presented as EN. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Maximum voluntary isometric contraction (MVIC) | 10 seconds | Maximum voluntary isometric contraction of each digit is measured for training reference. |
Countries
Taiwan
Outcome results
None listed