Effectiveness of Conventional Therapy Plus Pulsed-Radiofrequency for Herniated Nucleus Pulposus

Comparison of The Effectiveness Between Conventional Therapy and Conventional Therapy Plus Pulsed-Radiofrequency in Herniated Nucleus Pulposus Patients at Dr. Saiful Anwar Hospital, Malang

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT06415331

Enrollment

Registered

2024-05-16

Start date

2023-02-02

Completion date

2023-09-16

Last updated

2024-05-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Herniated Nucleus Pulposus, Pain

Brief summary

The purpose of this research was to study whether the additional application of a certain medical intervention making use of radiofrequencies (pulsed-radiofrequency) would reduce pain in patients with herniated disk.

Detailed description

Pain is an uncomfortable sensory and emotional experience that can affect quality of life. Low back pain (LBP) is one of the most common causes of pain, with herniated nucleus pulposus (HNP) being a common etiology. Pulsed radiofrequency (PRF) is a relatively novel technique that has shown promising results in many applications, including spinal pain conditions. This quasi-experimental study aimed to compare pain levels between patients who underwent conventional therapy (CT) alone and CT plus PRF as management in patients with HNP. Pain severity was measured in the numeric rating scale before and 1 month after treatment.

Interventions

PROCEDUREPulsed radiofrequency

Individualized dose of pulsed radiofrequency is given for 6 minutes.

OTHERConventional therapy

Conventional therapy for HNP consisting of: * Acetaminophen * NSAID: Etoricoxib, celecoxib, meloxicam, diclofenac, ibuprofen * Muscle relaxant: eperisone, diazepam * Opioid: codein, tramadol * Adjuvant analgesics: Amitriptyline, pregabalin, gabapentin * Physiotherapy: Short wave diathermy, ultrasound diathermy, transcutaneous electrical nerve stimulation, and exercise

Study design

Allocation

NON_RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to 80 Years

Healthy volunteers

Inclusion criteria

* Having an established diagnosis of HNP * Complaint present for at least the pas 3 months * Experiencing pain intensity of 4 or greater on the numeric rating scale * Capable of giving informed consent

Exclusion criteria

* Pregnant patients * Presence of infection at the site of pulsed radiofrequency * HNP with red flags.

Design outcomes

Primary

Measure	Time frame	Description
Pain severity	1 month after treatment	Pain severity measured with the numeric rating scale (NRS). The numeric rating scale measures pain on a scale of 0-10 with 0 representing no pain and 10 representing the worst pain possible.

Countries

Indonesia

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026