Hemodynamic Instability, Shock, Septic
Conditions
Brief summary
We evaluated the ability of shock indices and hemodynamic parameters to predict 28-day ICU mortality.
Detailed description
Shock indices and hemodynamic parameters are significant determinants of mortality in adult ICU patients. This study aimed to evaluate the potential of four known shock indices Shock Index (SI), Age-adjusted Shock Index (aSI), Diastolic Shock Index (dSI), and hemodynamic parameters including Heart Rate (HR), Systolic Arterial Blood Pressure (ABPsys), Diastolic Arterial Blood Pressure (ABPdias), and Mean Arterial Blood Pressure (ABPmean) in predicting 28-day ICU mortality in patients diagnosed with sepsis and septic shock.
Interventions
PROCEDUREMeasurement of hemodynamic parameters.
The measurement and recording of Heart Rate (HR), Systolic Arterial Blood Pressure (ABPsys), Diastolic Arterial Blood Pressure (ABPdias), Mean Arterial Blood Pressure (ABPmean), and age parameters.
Sponsors
SBÜ Dr. Sadi Konuk Eğitim ve Araştırma Hastanesi
Başakşehir Çam & Sakura City Hospital
Study design
Observational model
CASE_CONTROL
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 80 Years
Inclusion criteria
1. Patients with a preliminary diagnosis of sepsis/septic shock in the intensive care unit 2. Adult patients aged between 18 and 80 years
Exclusion criteria
1. Patients under 18 years old 2. Pregnant patients 3. Patients suspected of having COVID-19 pneumonia 4. Patients with incomplete data 5. Patients for whom outcome information is unavailable due to referral to an external center 6. Patients with confirmed COVID-19, validated by thoracic computed tomography images and nasal swab PCR results 7. Patients discharged from the intensive care unit within 24 hours
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Shock Index (SI) | During the first 7 hours in the ICU | The predictive power of the Shock Index (SI) parameter for 28-day mortality in sepsis patients treated in the intensive care unit. |
| Age-adjusted Shock Index (aSI) | During the first 7 hours in the ICU | The predictive power of the Age-adjusted Shock Index (aSI) parameter for 28-day mortality in sepsis patients treated in the intensive care unit. |
| Diastolic Shock Index (dSI) | During the first 7 hours in the ICU | The predictive power of the Diastolic Shock Index (dSI) parameter for 28-day mortality in sepsis patients treated in the intensive care unit. |
| modified Shock Index (mSI) | During the first 7 hours in the ICU | The predictive power of the modified Shock Index (mSI) parameter for 28-day mortality in sepsis patients treated in the intensive care unit. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Diastolic Arterial Blood Pressure (ABPdias) | During the first 7 hours in the ICU | The predictive power of the Diastolic Arterial Blood Pressure (ABPdias) parameter for 28-day mortality in sepsis patients treated in the intensive care unit. |
| Age | During the first 7 hours in the ICU | The predictive power of the age for 28-day mortality in sepsis patients treated in the intensive care unit. |
| Heart Rate (HR) | During the first 7 hours in the ICU | The predictive power of the Heart Rate (HR) parameter for 28-day mortality in sepsis patients treated in the intensive care unit. |
| Systolic Arterial Blood Pressure (ABPsys) | During the first 7 hours in the ICU | The predictive power of the Systolic Arterial Blood Pressure (ABPsys) parameter for 28-day mortality in sepsis patients treated in the intensive care unit. |
| Mean Arterial Blood Pressure (ABPmean) | During the first 7 hours in the ICU | The predictive power of the Mean Arterial Blood Pressure (ABPmean) parameter for 28-day mortality in sepsis patients treated in the intensive care unit. |
Countries
Turkey (Türkiye)
Outcome results
None listed