Comparing Mechanical Power in Different Inspiratory Times

Comparing Mechanical Power Values Using Geometric Methods at Different Inspiratory Rise and Pause Times: A Validation Study

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT06413472

Enrollment

Registered

2024-05-14

Start date

2024-03-01

Completion date

2024-06-01

Last updated

2025-07-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Respiratory Distress Syndrome, Ventilator-Induced Lung Injury

Brief summary

We aimed to compare mechanical power and energy values using geometric methods at varying inspiratory rise times.

Detailed description

In this study, the researchers aim to compare the mechanical power and energy values calculated using the geometric method in Volume-Controlled Ventilation (VCV) and Pressure-Controlled Ventilation (PCV) modes at different inspiratory rise times.

Interventions

PROCEDUREMechanical ventilator adjustment for PCV

In pressure control ventilation (PCV) mode, patients will be ventilated for 5 minutes at a Tslope of 5% and another 5 minutes at 15% for both 1:1 and 1:2 I:E ratios. After each adjustment, screenshots of the mechanical ventilator (P-V loop screenshots) will be obtained . A total of 20 P-V loop screenshots will be captured over a 20-minute period (10 for the 1:2 ratio and 10 for the 1:1 ratio), which will be stored in the ventilators memory. The stored data will then be transferred from the ventilators memory to a computer via a flash drive.

PROCEDUREMechanical ventilator adjustment for VCV

In volume control ventilation (VCV) mode, patients will be ventilated for 5 minutes at a Tslope of 5% and another 5 minutes at 15% for both 1:1 and 1:2 I:E ratios. After each adjustment, screenshots of the mechanical ventilator (P-V loop screenshots) will be obtained . A total of 20 P-V loop screenshots will be captured over a 20-minute period (10 for the 1:2 ratio and 10 for the 1:1 ratio), which will be stored in the ventilators memory. The stored data will then be transferred from the ventilators memory to a computer via a flash drive.

Study design

Observational model

CASE_CONTROL

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 80 Years

Healthy volunteers

Inclusion criteria

* ARDS (Acute Respiratory Distress Syndrome) patients. * Patients who are deeply sedated. * Patients ventilated in: * Pressure-Controlled Ventilation (PCV or PRVC) mode, or * Volume-Controlled Ventilation (VCV) mode. * Patients within the 24-48 hour period of their stay in the intensive care unit.

Exclusion criteria

* Patients with incomplete data. * Patients diagnosed with: * COPD (Chronic Obstructive Pulmonary Disease), * Heart failure. * Pregnant patients. * Patients with a thoracopleural fistula. * Hemodynamically unstable patients.

Design outcomes

Primary

Measure	Time frame	Description
MPgeo	40 minute	The mechanical power (MPgeo) values measured using the geometric method .
Energy	40 minute	Energy values measured using the geometric method .

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026