Skip to content

Adaptive Response of Brain Towards Resistance Training in Healthy Individuals

Adaptive Response of Brain Towards Resistance Training in Healthy Individuals

Status
Completed
Phases
Unknown
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT06413199
Enrollment
104
Registered
2024-05-14
Start date
2023-08-18
Completion date
2024-09-30
Last updated
2026-09-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Resistance Training

Keywords

Resistance Training, Performance, Nervous Response, Muscle growth, Exercise Induced Performance

Brief summary

The novelty of this study is to identify the mechanism of nervous system by applying resistance training intervention in healthy individuals.

Detailed description

Resistance training is a form of exercise that is popular particularly for its role in improving athletic performance by increasing muscular strength, power and speed, hypertrophy, local muscular endurance, motor performance, balance and coordination. The objective of the study is to find out the effects of resistance training on Central and Peripheral Nervous System in healthy individuals. A total of 100 participants will be included in the study including both male and female. The study will be divided into two main groups. Experimental group will perform 8-12 Reps with 1.5 sec concentric and 1.5 sec eccentric contraction of bench press with 90 sec of rest between sets with 2 sets per week for 2 months. 1RM of control group will be calculated through the same method and the training protocol for the Control group consisted of 5 attempts to lift as much weight as possible one time for that training visit with 90 seconds of rest between attempts. The load was progressively increased each attempt to try to reach or exceed their previous 1RM.

Interventions

OTHERHyper Training

Experimental group will perform 2 training session per week for 2 months, 1 set of 10 unloaded repetitions in arms as a warm-up, 4 sets with a goal of 8-12 Reps with 90 seconds rest between sets. 1.5 second concentric and 1.5 second eccentric contraction of bench press, The elbows had to be fully locked out to be counted as a repetition.

OTHER1 Repetition maximum training group

2 training session per week for 8 weeks, 1 set of 10 unloaded repetitions in arms as a warm-up, 1 Repetition maximum training group consisted of 5 attempts to lift as much weight as possible one time for that training visit with 90 seconds of rest between attempts, the load was progressively increased each attempt to try to reach or exceed their previous 1 repetition maximum.

Sponsors

Pakistan Society for Rehabilitation of Differently Abled Hospital
Lead SponsorOTHER
University of Karachi
CollaboratorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Investigator)

Eligibility

Sex/Gender
ALL
Age
18 Years to 35 Years
Healthy volunteers
Yes

Inclusion criteria

* Body Mass Index should be 18.5-24.9 kg/m2. * Participants were untrained and had not engaged in resistance exercise within 6 months prior to beginning the study.

Exclusion criteria

* Participants with any kind of Gastrointestinal Tract disturbance will be excluded from the study. * Participants with any kind of Musculoskeletal injury will be excluded from the study. * Participant with any kind of Neurological disturbance will be excluded from the study. * Participants who use tobacco products within the previous 6 months. * Participants who take any type of medication within the previous 6 months.

Design outcomes

Primary

MeasureTime frameDescription
NCS (Motor Nerve Conduction Study)• 0 week • 8th weekTo determine how fast or slow the nerves are conducting an electrical current using F wave
EEG (Electroencephalography)• 0 week • 8th weekTo measure the electrical activity of the brain using alpha and beta waves
Dynamometer• 0 week • 4th week • 8th weekTo measure the strength after resistance training
Estimation of Albumin & Globulin ratio• 0 week • 8th weekTo measure the total amount of protein in blood and effects of resistance training

Countries

Pakistan

Contacts

PRINCIPAL_INVESTIGATORDanish Latif, PhD*

PSRD College of Rehabilitation Sciences

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Sep 2, 2026