Cluster Headache
Conditions
Brief summary
Since there is conflicting and insufficient data regarding CH personality and addictive behaviour, the investigators will investigate risk- and reward seeking behaviour in people with cluster headache. If an increased tendency towards this behaviour is shown, it will add to the clinical knowledge of cluster headache and possible lead to insights in a common biological susceptibility.
Detailed description
Cluster headache is a severe primary headache disorder. In clinical anecdotes, people with cluster headache frequently report use of tobacco and illicit drugs. Furthermore, addictive behaviours and tattoos are considered to be more common in people with cluster headache than in the general population. The causality of these associations remains unclear. A common biological susceptibility has been proposed, predisposing people to both addictive behaviour and cluster headache. On the other hand, a role of illicit drug exposure in cluster headache pathophysiology has been suggested. The increased use of tobacco and illicit drugs could also reflect attempts to treat cluster headache attacks. In this explorative study the investigators will assess both subjective and objective measures reflecting addictive behaviour and risk- and reward seeking in cluster headache. This will add to the clinical knowledge of cluster headache and possible lead to insights in a common biological susceptibility.
Interventions
DIAGNOSTIC_TESTBART Task
The Zuckerman's Sensation Seeking Scale version-V (SSS-V) - Four-factor score, The Barret Impulsiveness Scale (BIS), Gormally's Binge Eating Scale (BES), The World Health Organization-developed AUDIT (Alcohol Use Disorders Identification Test) screen, The CAGE questionnaire for substance abuse-adapted to include drugs, Gamblers Anonymous's 20 Questions (GA20), Hospital Anxiety and Depression Scale (HADS)
Sponsors
Leiden University Medical Center
Study design
Observational model
CASE_CONTROL
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
Yes
Inclusion criteria
* Age 18-64 years * Normal or corrected vision with acuity up to 20/60 * Presence of episodic (n=35) or chronic (n=35) cluster headache or migraine with or without arua (n=35), diagnosed according to the International Classification of Headache Disorders criteria, 3rd edition (ICHD-3, 3.1.1)
Exclusion criteria
* Diagnosis of uncorrected visual problems (myopia/presbiopia, peripheral vision problems or legal blindness) * Current diagnosis of generalized anxiety disorder, depression or other psychiatric illness * Other acute, unstable medical conditions or serious chronic diagnoses
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Difference in mean total score on the Zuckerman Sensation Seeking Scale between groups | One time-point | Between group difference |
| Difference in mean total number of pumps during second trial between groups | One time-point | Between group difference |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Difference in mean scores on the array of psychometric tests between groups | One time-point | Between group difference |
| Difference in mean scores on the BART between groups and between the first and second BART within groups | One time-point | Average # of pumps, Exploded Balloons |
Countries
Netherlands
Outcome results
None listed