Bone Sarcoma, Soft Tissue Sarcoma
Conditions
Brief summary
This study evaluates the effectiveness of intraoperative indocyanine green dye and fluoroscopic technology in confirming negative margins after tumor removal.
Detailed description
PRIMARY OBJECTIVE: I. To evaluate the use of indocyanine green (ICG) as an intraoperative guide during bone and soft tissue sarcoma resection. OUTLINE: This is an observational study. Patients receive ICG infusion prior to undergoing scheduled resection and have medical records reviewed on study.
Interventions
OTHERNon-Interventional Study
Non-interventional study
Sponsors
Mayo Clinic
Study design
Observational model
COHORT
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patients with biopsy-proven bone or soft tissue sarcoma undergoing resection
Exclusion criteria
* Chronic kidney disease * Anaphylaxis to dyes
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Accuracy of intraoperative ICG fluorescence compared to final pathology results | Baseline | Intraoperative ICG fluorescence and deduced margins will be analyzed and compared the accuracy to final pathology margins. Negative predictive value will be calculated. |
Countries
United States
Contacts
CONTACTClinical Trials Referral Office
CONTACTLaura Dohrmann
PRINCIPAL_INVESTIGATORMatthew T. Houdek, M.D.
Mayo Clinic in Rochester
Outcome results
None listed